Burke KA - Search Results

1

Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein.

Nucifora LG, Burke KA, Feng X, Arbez N, Zhu S, Miller J, Yang G, Ratovitski T, Delannoy M, Muchowski PJ, Finkbeiner S, Legleiter J, Ross CA, Poirier MA. Nucifora LG, et al. Among authors: burke ka. J Biol Chem. 2012 May 4;287(19):16017-28. doi: 10.1074/jbc.M111.252577. Epub 2012 Mar 20. J Biol Chem. 2012. PMID: 22433867 Free PMC article.

2

The interaction of polyglutamine peptides with lipid membranes is regulated by flanking sequences associated with huntingtin.

Burke KA, Kauffman KJ, Umbaugh CS, Frey SL, Legleiter J. Burke KA, et al. J Biol Chem. 2013 May 24;288(21):14993-5005. doi: 10.1074/jbc.M112.446237. Epub 2013 Apr 9. J Biol Chem. 2013. PMID: 23572526 Free PMC article.

3

Atomic force microscopy assays for evaluating polyglutamine aggregation in solution and on surfaces.

Burke KA, Legleiter J. Burke KA, et al. Methods Mol Biol. 2013;1017:21-40. doi: 10.1007/978-1-62703-438-8_2. Methods Mol Biol. 2013. PMID: 23719905

4

Assessing mutant huntingtin fragment and polyglutamine aggregation by atomic force microscopy.

Burke KA, Godbey J, Legleiter J. Burke KA, et al. Methods. 2011 Mar;53(3):275-84. doi: 10.1016/j.ymeth.2010.12.028. Epub 2010 Dec 25. Methods. 2011. PMID: 21187152

5

Curvature enhances binding and aggregation of huntingtin at lipid membranes.

Chaibva M, Burke KA, Legleiter J. Chaibva M, et al. Among authors: burke ka. Biochemistry. 2014 Apr 15;53(14):2355-65. doi: 10.1021/bi401619q. Epub 2014 Apr 4. Biochemistry. 2014. PMID: 24670006

6

Huntingtin disrupts lipid bilayers in a polyQ-length dependent manner.

Burke KA, Hensal KM, Umbaugh CS, Chaibva M, Legleiter J. Burke KA, et al. Biochim Biophys Acta. 2013 Aug;1828(8):1953-61. doi: 10.1016/j.bbamem.2013.04.025. Epub 2013 May 2. Biochim Biophys Acta. 2013. PMID: 23643759 Free article.

7

Lysine residues in the N-terminal huntingtin amphipathic α-helix play a key role in peptide aggregation.

Arndt JR, Brown RJ, Burke KA, Legleiter J, Valentine SJ. Arndt JR, et al. Among authors: burke ka. J Mass Spectrom. 2015 Jan;50(1):117-26. doi: 10.1002/jms.3504. J Mass Spectrom. 2015. PMID: 25601683

8

Biophysical insights into how surfaces, including lipid membranes, modulate protein aggregation related to neurodegeneration.

Burke KA, Yates EA, Legleiter J. Burke KA, et al. Front Neurol. 2013 Mar 1;4:17. doi: 10.3389/fneur.2013.00017. eCollection 2013. Front Neurol. 2013. PMID: 23459674 Free PMC article.

9

Amyloid-forming proteins alter the local mechanical properties of lipid membranes.

Burke KA, Yates EA, Legleiter J. Burke KA, et al. Biochemistry. 2013 Feb 5;52(5):808-17. doi: 10.1021/bi301070v. Epub 2013 Jan 27. Biochemistry. 2013. PMID: 23331195

10

Mapping the mechanical properties of cholesterol-containing supported lipid bilayers with nanoscale spatial resolution.

Shamitko-Klingensmith N, Molchanoff KM, Burke KA, Magnone GJ, Legleiter J. Shamitko-Klingensmith N, et al. Among authors: burke ka. Langmuir. 2012 Sep 18;28(37):13411-22. doi: 10.1021/la302705f. Epub 2012 Sep 5. Langmuir. 2012. PMID: 22924735

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