Finkbeiner S - Search Results

1

Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein.

Nucifora LG, Burke KA, Feng X, Arbez N, Zhu S, Miller J, Yang G, Ratovitski T, Delannoy M, Muchowski PJ, Finkbeiner S, Legleiter J, Ross CA, Poirier MA. Nucifora LG, et al. Among authors: finkbeiner s. J Biol Chem. 2012 May 4;287(19):16017-28. doi: 10.1074/jbc.M111.252577. Epub 2012 Mar 20. J Biol Chem. 2012. PMID: 22433867 Free PMC article.

2

Monoclonal antibodies recognize distinct conformational epitopes formed by polyglutamine in a mutant huntingtin fragment.

Legleiter J, Lotz GP, Miller J, Ko J, Ng C, Williams GL, Finkbeiner S, Patterson PH, Muchowski PJ. Legleiter J, et al. Among authors: finkbeiner s. J Biol Chem. 2009 Aug 7;284(32):21647-58. doi: 10.1074/jbc.M109.016923. Epub 2009 Jun 2. J Biol Chem. 2009. PMID: 19491400 Free PMC article.

3

A compact beta model of huntingtin toxicity.

Zhang QC, Yeh TL, Leyva A, Frank LG, Miller J, Kim YE, Langen R, Finkbeiner S, Amzel ML, Ross CA, Poirier MA. Zhang QC, et al. Among authors: finkbeiner s. J Biol Chem. 2011 Mar 11;286(10):8188-8196. doi: 10.1074/jbc.M110.192013. Epub 2011 Jan 5. J Biol Chem. 2011. PMID: 21209075 Free PMC article.

4

Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models.

Sontag EM, Lotz GP, Agrawal N, Tran A, Aron R, Yang G, Necula M, Lau A, Finkbeiner S, Glabe C, Marsh JL, Muchowski PJ, Thompson LM. Sontag EM, et al. Among authors: finkbeiner s. J Neurosci. 2012 Aug 8;32(32):11109-19. doi: 10.1523/JNEUROSCI.0895-12.2012. J Neurosci. 2012. PMID: 22875942 Free PMC article.

5

Identical oligomeric and fibrillar structures captured from the brains of R6/2 and knock-in mouse models of Huntington's disease.

Sathasivam K, Lane A, Legleiter J, Warley A, Woodman B, Finkbeiner S, Paganetti P, Muchowski PJ, Wilson S, Bates GP. Sathasivam K, et al. Among authors: finkbeiner s. Hum Mol Genet. 2010 Jan 1;19(1):65-78. doi: 10.1093/hmg/ddp467. Hum Mol Genet. 2010. PMID: 19825844 Free PMC article.

6

Identifying polyglutamine protein species in situ that best predict neurodegeneration.

Miller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, Osmand A, Gray M, Thulasiramin V, Saudou F, Segal M, Yang XW, Masliah E, Thompson LM, Muchowski PJ, Weisgraber KH, Finkbeiner S. Miller J, et al. Among authors: finkbeiner s. Nat Chem Biol. 2011 Oct 30;7(12):925-34. doi: 10.1038/nchembio.694. Nat Chem Biol. 2011. PMID: 22037470 Free PMC article.

7

Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes.

HD iPSC Consortium. HD iPSC Consortium. Cell Stem Cell. 2012 Aug 3;11(2):264-78. doi: 10.1016/j.stem.2012.04.027. Epub 2012 Jun 28. Cell Stem Cell. 2012. PMID: 22748968 Free PMC article.

8

Conformation sensors that distinguish monomeric proteins from oligomers in live cells.

Ramdzan YM, Nisbet RM, Miller J, Finkbeiner S, Hill AF, Hatters DM. Ramdzan YM, et al. Among authors: finkbeiner s. Chem Biol. 2010 Apr 23;17(4):371-9. doi: 10.1016/j.chembiol.2010.03.011. Chem Biol. 2010. PMID: 20416508 Free PMC article.

9

αB-Crystallin overexpression in astrocytes modulates the phenotype of the BACHD mouse model of Huntington's disease.

Oliveira AO, Osmand A, Outeiro TF, Muchowski PJ, Finkbeiner S. Oliveira AO, et al. Among authors: finkbeiner s. Hum Mol Genet. 2016 May 1;25(9):1677-89. doi: 10.1093/hmg/ddw028. Epub 2016 Feb 26. Hum Mol Genet. 2016. PMID: 26920069 Free PMC article.

10

Quantitative relationships between huntingtin levels, polyglutamine length, inclusion body formation, and neuronal death provide novel insight into huntington's disease molecular pathogenesis.

Miller J, Arrasate M, Shaby BA, Mitra S, Masliah E, Finkbeiner S. Miller J, et al. Among authors: finkbeiner s. J Neurosci. 2010 Aug 4;30(31):10541-50. doi: 10.1523/JNEUROSCI.0146-10.2010. J Neurosci. 2010. PMID: 20685997 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

239 results

Search Page

Filters