Wang J - Search Results

1

Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme.

Wang J, Friedman G, Doyon Y, Wang NS, Li CJ, Miller JC, Hua KL, Yan JJ, Babiarz JE, Gregory PD, Holmes MC. Wang J, et al. Among authors: wang ns. Genome Res. 2012 Jul;22(7):1316-26. doi: 10.1101/gr.122879.111. Epub 2012 Mar 20. Genome Res. 2012. PMID: 22434427 Free PMC article.

2

An improved zinc-finger nuclease architecture for highly specific genome editing.

Miller JC, Holmes MC, Wang J, Guschin DY, Lee YL, Rupniewski I, Beausejour CM, Waite AJ, Wang NS, Kim KA, Gregory PD, Pabo CO, Rebar EJ. Miller JC, et al. Among authors: wang j, wang ns. Nat Biotechnol. 2007 Jul;25(7):778-85. doi: 10.1038/nbt1319. Epub 2007 Jul 1. Nat Biotechnol. 2007. PMID: 17603475

3

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures.

Doyon Y, Vo TD, Mendel MC, Greenberg SG, Wang J, Xia DF, Miller JC, Urnov FD, Gregory PD, Holmes MC. Doyon Y, et al. Among authors: wang j. Nat Methods. 2011 Jan;8(1):74-9. doi: 10.1038/nmeth.1539. Epub 2010 Dec 5. Nat Methods. 2011. PMID: 21131970

4

A TALE nuclease architecture for efficient genome editing.

Miller JC, Tan S, Qiao G, Barlow KA, Wang J, Xia DF, Meng X, Paschon DE, Leung E, Hinkley SJ, Dulay GP, Hua KL, Ankoudinova I, Cost GJ, Urnov FD, Zhang HS, Holmes MC, Zhang L, Gregory PD, Rebar EJ. Miller JC, et al. Among authors: wang j. Nat Biotechnol. 2011 Feb;29(2):143-8. doi: 10.1038/nbt.1755. Epub 2010 Dec 22. Nat Biotechnol. 2011. PMID: 21179091

5

Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases.

Liu PQ, Chan EM, Cost GJ, Zhang L, Wang J, Miller JC, Guschin DY, Reik A, Holmes MC, Mott JE, Collingwood TN, Gregory PD. Liu PQ, et al. Among authors: wang j. Biotechnol Bioeng. 2010 May 1;106(1):97-105. doi: 10.1002/bit.22654. Biotechnol Bioeng. 2010. PMID: 20047187

6

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo.

Holt N, Wang J, Kim K, Friedman G, Wang X, Taupin V, Crooks GM, Kohn DB, Gregory PD, Holmes MC, Cannon PM. Holt N, et al. Among authors: wang x, wang j. Nat Biotechnol. 2010 Aug;28(8):839-47. doi: 10.1038/nbt.1663. Epub 2010 Jul 2. Nat Biotechnol. 2010. PMID: 20601939 Free PMC article.

7

Targeted correction and restored function of the CFTR gene in cystic fibrosis induced pluripotent stem cells.

Crane AM, Kramer P, Bui JH, Chung WJ, Li XS, Gonzalez-Garay ML, Hawkins F, Liao W, Mora D, Choi S, Wang J, Sun HC, Paschon DE, Guschin DY, Gregory PD, Kotton DN, Holmes MC, Sorscher EJ, Davis BR. Crane AM, et al. Among authors: wang j. Stem Cell Reports. 2015 Apr 14;4(4):569-77. doi: 10.1016/j.stemcr.2015.02.005. Epub 2015 Mar 12. Stem Cell Reports. 2015. PMID: 25772471 Free PMC article.

8

Highly efficient homology-driven genome editing in human T cells by combining zinc-finger nuclease mRNA and AAV6 donor delivery.

Wang J, DeClercq JJ, Hayward SB, Li PW, Shivak DA, Gregory PD, Lee G, Holmes MC. Wang J, et al. Nucleic Acids Res. 2016 Feb 18;44(3):e30. doi: 10.1093/nar/gkv1121. Epub 2015 Nov 2. Nucleic Acids Res. 2016. PMID: 26527725 Free PMC article.

9

Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors.

Wang J, Exline CM, DeClercq JJ, Llewellyn GN, Hayward SB, Li PW, Shivak DA, Surosky RT, Gregory PD, Holmes MC, Cannon PM. Wang J, et al. Nat Biotechnol. 2015 Dec;33(12):1256-1263. doi: 10.1038/nbt.3408. Epub 2015 Nov 9. Nat Biotechnol. 2015. PMID: 26551060 Free PMC article.

10

Long-term multilineage engraftment of autologous genome-edited hematopoietic stem cells in nonhuman primates.

Peterson CW, Wang J, Norman KK, Norgaard ZK, Humbert O, Tse CK, Yan JJ, Trimble RG, Shivak DA, Rebar EJ, Gregory PD, Holmes MC, Kiem HP. Peterson CW, et al. Among authors: wang j. Blood. 2016 May 19;127(20):2416-26. doi: 10.1182/blood-2015-09-672337. Epub 2016 Mar 15. Blood. 2016. PMID: 26980728 Free PMC article.

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