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Synthesis, biological evaluation and molecular modelling of N-heterocyclic dipeptide aldehydes as selective calpain inhibitors.
Jones MA, Morton JD, Coxon JM, McNabb SB, Lee HY, Aitken SG, Mehrtens JM, Robertson LJ, Neffe AT, Miyamoto S, Bickerstaffe R, Gately K, Wood JM, Abell AD. Jones MA, et al. Among authors: abell ad. Bioorg Med Chem. 2008 Jul 15;16(14):6911-23. doi: 10.1016/j.bmc.2008.05.048. Epub 2008 May 27. Bioorg Med Chem. 2008. PMID: 18571418
A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity.
Stanley NJ, Hutchinson MR, Kvist T, Nielsen B, Mathiesen JM, Bräuner-Osborne H, Avery TD, Tiekink ER, Pedersen DS, Irvine RJ, Abell AD, Taylor DK. Stanley NJ, et al. Among authors: abell ad. Bioorg Med Chem. 2010 Aug 15;18(16):6089-98. doi: 10.1016/j.bmc.2010.06.051. Epub 2010 Jun 25. Bioorg Med Chem. 2010. PMID: 20638290
1,2,3-triazolyl amino acids as AMPA receptor ligands.
Stanley NJ, Pedersen DS, Nielsen B, Kvist T, Mathiesen JM, Bräuner-Osborne H, Taylor DK, Abell AD. Stanley NJ, et al. Among authors: abell ad. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7512-5. doi: 10.1016/j.bmcl.2010.09.139. Epub 2010 Oct 14. Bioorg Med Chem Lett. 2010. PMID: 21036612
Selective inhibition of biotin protein ligase from Staphylococcus aureus.
Soares da Costa TP, Tieu W, Yap MY, Pendini NR, Polyak SW, Sejer Pedersen D, Morona R, Turnidge JD, Wallace JC, Wilce MCJ, Booker GW, Abell AD. Soares da Costa TP, et al. Among authors: abell ad. J Biol Chem. 2012 May 18;287(21):17823-17832. doi: 10.1074/jbc.M112.356576. Epub 2012 Mar 21. J Biol Chem. 2012. PMID: 22437830 Free PMC article.
180 results