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A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcγRIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques.
Moldt B, Shibata-Koyama M, Rakasz EG, Schultz N, Kanda Y, Dunlop DC, Finstad SL, Jin C, Landucci G, Alpert MD, Dugast AS, Parren PW, Nimmerjahn F, Evans DT, Alter G, Forthal DN, Schmitz JE, Iida S, Poignard P, Watkins DI, Hessell AJ, Burton DR. Moldt B, et al. Among authors: watkins di. J Virol. 2012 Jun;86(11):6189-96. doi: 10.1128/JVI.00491-12. Epub 2012 Mar 28. J Virol. 2012. PMID: 22457527 Free PMC article.
Effective induction of simian immunodeficiency virus-specific cytotoxic T lymphocytes in macaques by using a multiepitope gene and DNA prime-modified vaccinia virus Ankara boost vaccination regimen.
Hanke T, Samuel RV, Blanchard TJ, Neumann VC, Allen TM, Boyson JE, Sharpe SA, Cook N, Smith GL, Watkins DI, Cranage MP, McMichael AJ. Hanke T, et al. Among authors: watkins di. J Virol. 1999 Sep;73(9):7524-32. doi: 10.1128/JVI.73.9.7524-7532.1999. J Virol. 1999. PMID: 10438842 Free PMC article.
Definition of five new simian immunodeficiency virus cytotoxic T-lymphocyte epitopes and their restricting major histocompatibility complex class I molecules: evidence for an influence on disease progression.
Evans DT, Jing P, Allen TM, O'Connor DH, Horton H, Venham JE, Piekarczyk M, Dzuris J, Dykhuzen M, Mitchen J, Rudersdorf RA, Pauza CD, Sette A, Bontrop RE, DeMars R, Watkins DI. Evans DT, et al. Among authors: watkins di. J Virol. 2000 Aug;74(16):7400-10. doi: 10.1128/jvi.74.16.7400-7410.2000. J Virol. 2000. PMID: 10906193 Free PMC article.
CD8(+) lymphocytes from simian immunodeficiency virus-infected rhesus macaques recognize 14 different epitopes bound by the major histocompatibility complex class I molecule mamu-A*01: implications for vaccine design and testing.
Allen TM, Mothé BR, Sidney J, Jing P, Dzuris JL, Liebl ME, Vogel TU, O'Connor DH, Wang X, Wussow MC, Thomson JA, Altman JD, Watkins DI, Sette A. Allen TM, et al. Among authors: watkins di. J Virol. 2001 Jan;75(2):738-49. doi: 10.1128/JVI.75.2.738-749.2001. J Virol. 2001. PMID: 11134287 Free PMC article.
Impairment of Gag-specific CD8(+) T-cell function in mucosal and systemic compartments of simian immunodeficiency virus mac251- and simian-human immunodeficiency virus KU2-infected macaques.
Hel Z, Nacsa J, Kelsall B, Tsai WP, Letvin N, Parks RW, Tryniszewska E, Picker L, Lewis MG, Edghill-Smith Y, Moniuszko M, Pal R, Stevceva L, Altman JD, Allen TM, Watkins D, Torres JV, Berzofsky JA, Belyakov IM, Strober W, Franchini G. Hel Z, et al. J Virol. 2001 Dec;75(23):11483-95. doi: 10.1128/JVI.75.23.11483-11495.2001. J Virol. 2001. PMID: 11689630 Free PMC article.
Dominance of CD8 responses specific for epitopes bound by a single major histocompatibility complex class I molecule during the acute phase of viral infection.
Mothé BR, Horton H, Carter DK, Allen TM, Liebl ME, Skinner P, Vogel TU, Fuenger S, Vielhuber K, Rehrauer W, Wilson N, Franchini G, Altman JD, Haase A, Picker LJ, Allison DB, Watkins DI. Mothé BR, et al. Among authors: watkins di. J Virol. 2002 Jan;76(2):875-84. doi: 10.1128/jvi.76.2.875-884.2002. J Virol. 2002. PMID: 11752176 Free PMC article.
Induction of anti-simian immunodeficiency virus cellular and humoral immune responses in rhesus macaques by peptide immunogens: correlation of CTL activity and reduction of cell-associated but not plasma virus load following challenge.
Vogel TU, Beer BE, Zur Megede J, Ihlenfeldt HG, Jung G, Holzammer S, Watkins DI, Altman JD, Kurth R, Norley S. Vogel TU, et al. Among authors: watkins di. J Gen Virol. 2002 Jan;83(Pt 1):81-91. doi: 10.1099/0022-1317-83-1-81. J Gen Virol. 2002. PMID: 11752704
Tat-vaccinated macaques do not control simian immunodeficiency virus SIVmac239 replication.
Allen TM, Mortara L, Mothé BR, Liebl M, Jing P, Calore B, Piekarczyk M, Ruddersdorf R, O'Connor DH, Wang X, Wang C, Allison DB, Altman JD, Sette A, Desrosiers RC, Sutter G, Watkins DI. Allen TM, et al. Among authors: watkins di. J Virol. 2002 Apr;76(8):4108-12. doi: 10.1128/jvi.76.8.4108-4112.2002. J Virol. 2002. PMID: 11907251 Free PMC article.
266 results