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Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin.
Gardenghi S, Marongiu MF, Ramos P, Guy E, Breda L, Chadburn A, Liu Y, Amariglio N, Rechavi G, Rachmilewitz EA, Breuer W, Cabantchik ZI, Wrighting DM, Andrews NC, de Sousa M, Giardina PJ, Grady RW, Rivella S. Gardenghi S, et al. Among authors: rivella s. Blood. 2007 Jun 1;109(11):5027-35. doi: 10.1182/blood-2006-09-048868. Epub 2007 Feb 13. Blood. 2007. PMID: 17299088 Free PMC article.
Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemia.
Libani IV, Guy EC, Melchiori L, Schiro R, Ramos P, Breda L, Scholzen T, Chadburn A, Liu Y, Kernbach M, Baron-Lühr B, Porotto M, de Sousa M, Rachmilewitz EA, Hood JD, Cappellini MD, Giardina PJ, Grady RW, Gerdes J, Rivella S. Libani IV, et al. Among authors: rivella s. Blood. 2008 Aug 1;112(3):875-85. doi: 10.1182/blood-2007-12-126938. Epub 2008 May 14. Blood. 2008. PMID: 18480424 Free PMC article.
Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations.
Salvatori F, Cantale V, Breveglieri G, Zuccato C, Finotti A, Bianchi N, Borgatti M, Feriotto G, Destro F, Canella A, Breda L, Rivella S, Gambari R. Salvatori F, et al. Among authors: rivella s. Biotechnol Appl Biochem. 2009 Jul 9;54(1):41-52. doi: 10.1042/BA20080266. Biotechnol Appl Biochem. 2009. PMID: 19216718 Free PMC article.
Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients.
Salvatori F, Breveglieri G, Zuccato C, Finotti A, Bianchi N, Borgatti M, Feriotto G, Destro F, Canella A, Brognara E, Lampronti I, Breda L, Rivella S, Gambari R. Salvatori F, et al. Among authors: rivella s. Am J Hematol. 2009 Nov;84(11):720-8. doi: 10.1002/ajh.21539. Am J Hematol. 2009. PMID: 19810011 Free PMC article.
158 results