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Clinical significance of stromal apoptosis in colorectal cancer.
Koelink PJ, Sier CF, Hommes DW, Lamers CB, Verspaget HW. Koelink PJ, et al. Among authors: hommes dw. Br J Cancer. 2009 Sep 1;101(5):765-73. doi: 10.1038/sj.bjc.6605220. Epub 2009 Aug 4. Br J Cancer. 2009. PMID: 19654576 Free PMC article.
The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC.
Voorneveld PW, Kodach LL, Jacobs RJ, van Noesel CJ, Peppelenbosch MP, Korkmaz KS, Molendijk I, Dekker E, Morreau H, van Pelt GW, Tollenaar RA, Mesker W, Hawinkels LJ, Paauwe M, Verspaget HW, Geraets DT, Hommes DW, Offerhaus GJ, van den Brink GR, Ten Dijke P, Hardwick JC. Voorneveld PW, et al. Among authors: hommes dw. Br J Cancer. 2015 Jan 6;112(1):122-30. doi: 10.1038/bjc.2014.560. Epub 2014 Nov 13. Br J Cancer. 2015. PMID: 25393365 Free PMC article.
Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway.
Kodach LL, Jacobs RJ, Voorneveld PW, Wildenberg ME, Verspaget HW, van Wezel T, Morreau H, Hommes DW, Peppelenbosch MP, van den Brink GR, Hardwick JC. Kodach LL, et al. Among authors: hommes dw. Gut. 2011 Nov;60(11):1544-53. doi: 10.1136/gut.2011.237495. Epub 2011 May 6. Gut. 2011. PMID: 21551187
254 results