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Direct Thy-1/alphaVbeta3 integrin interaction mediates neuron to astrocyte communication.
Hermosilla T, Muñoz D, Herrera-Molina R, Valdivia A, Muñoz N, Nham SU, Schneider P, Burridge K, Quest AF, Leyton L. Hermosilla T, et al. Among authors: schneider p. Biochim Biophys Acta. 2008 Jun;1783(6):1111-20. doi: 10.1016/j.bbamcr.2008.01.034. Epub 2008 Feb 20. Biochim Biophys Acta. 2008. PMID: 18346467 Free PMC article.
Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alphavbeta3 integrin that activates PKCalpha and RhoA.
Avalos AM, Valdivia AD, Muñoz N, Herrera-Molina R, Tapia JC, Lavandero S, Chiong M, Burridge K, Schneider P, Quest AF, Leyton L. Avalos AM, et al. Among authors: schneider p. J Cell Sci. 2009 Oct 1;122(Pt 19):3462-71. doi: 10.1242/jcs.034827. Epub 2009 Sep 1. J Cell Sci. 2009. PMID: 19723805 Free PMC article.
αVβ3 Integrin regulates astrocyte reactivity.
Lagos-Cabré R, Alvarez A, Kong M, Burgos-Bravo F, Cárdenas A, Rojas-Mancilla E, Pérez-Nuñez R, Herrera-Molina R, Rojas F, Schneider P, Herrera-Marschitz M, Quest AFG, van Zundert B, Leyton L. Lagos-Cabré R, et al. Among authors: schneider p. J Neuroinflammation. 2017 Sep 29;14(1):194. doi: 10.1186/s12974-017-0968-5. J Neuroinflammation. 2017. PMID: 28962574 Free PMC article.
Astrocyte-to-neuron communication through integrin-engaged Thy-1/CBP/Csk/Src complex triggers neurite retraction via the RhoA/ROCK pathway.
Maldonado H, Calderon C, Burgos-Bravo F, Kobler O, Zuschratter W, Ramirez O, Härtel S, Schneider P, Quest AF, Herrera-Molina R, Leyton L. Maldonado H, et al. Among authors: schneider p. Biochim Biophys Acta Mol Cell Res. 2017 Feb;1864(2):243-254. doi: 10.1016/j.bbamcr.2016.11.006. Epub 2016 Nov 12. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 27842221 Free article.
Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells.
Valdivia A, Cárdenas A, Brenet M, Maldonado H, Kong M, Díaz J, Burridge K, Schneider P, San Martín A, García-Mata R, Quest AFG, Leyton L. Valdivia A, et al. Among authors: schneider p. Cell Commun Signal. 2020 Aug 18;18(1):129. doi: 10.1186/s12964-020-00629-3. Cell Commun Signal. 2020. PMID: 32811537 Free PMC article.
3,128 results