Svendsen A - Search Results

1

Single enzyme studies reveal the existence of discrete functional states for monomeric enzymes and how they are "selected" upon allosteric regulation.

Hatzakis NS, Wei L, Jorgensen SK, Kunding AH, Bolinger PY, Ehrlich N, Makarov I, Skjot M, Svendsen A, Hedegård P, Stamou D. Hatzakis NS, et al. Among authors: svendsen a. J Am Chem Soc. 2012 Jun 6;134(22):9296-302. doi: 10.1021/ja3011429. Epub 2012 May 21. J Am Chem Soc. 2012. PMID: 22489643 Free article.

2

Direct observation of Thermomyces lanuginosus lipase diffusional states by Single Particle Tracking and their remodeling by mutations and inhibition.

Bohr SS, Lund PM, Kallenbach AS, Pinholt H, Thomsen J, Iversen L, Svendsen A, Christensen SM, Hatzakis NS. Bohr SS, et al. Among authors: svendsen a. Sci Rep. 2019 Nov 7;9(1):16169. doi: 10.1038/s41598-019-52539-1. Sci Rep. 2019. PMID: 31700110 Free PMC article.

3

Synthesis and single enzyme activity of a clicked lipase-BSA hetero-dimer.

Hatzakis NS, Engelkamp H, Velonia K, Hofkens J, Christianen PC, Svendsen A, Patkar SA, Vind J, Maan JC, Rowan AE, Nolte RJ. Hatzakis NS, et al. Among authors: svendsen a. Chem Commun (Camb). 2006 May 21;(19):2012-4. doi: 10.1039/b516551b. Epub 2006 Feb 9. Chem Commun (Camb). 2006. PMID: 16767259

4

Bionanoconjugation via click chemistry: The creation of functional hybrids of lipases and gold nanoparticles.

Brennan JL, Hatzakis NS, Tshikhudo TR, Dirvianskyte N, Razumas V, Patkar S, Vind J, Svendsen A, Nolte RJ, Rowan AE, Brust M. Brennan JL, et al. Among authors: svendsen a. Bioconjug Chem. 2006 Nov-Dec;17(6):1373-5. doi: 10.1021/bc0601018. Bioconjug Chem. 2006. PMID: 17105213

5

Understanding the plasticity of the alpha/beta hydrolase fold: lid swapping on the Candida antarctica lipase B results in chimeras with interesting biocatalytic properties.

Skjøt M, De Maria L, Chatterjee R, Svendsen A, Patkar SA, Ostergaard PR, Brask J. Skjøt M, et al. Among authors: svendsen a. Chembiochem. 2009 Feb 13;10(3):520-7. doi: 10.1002/cbic.200800668. Chembiochem. 2009. PMID: 19156649

6

Linking phospholipase mobility to activity by single-molecule wide-field microscopy.

Rocha S, Hutchison JA, Peneva K, Herrmann A, Müllen K, Skjøt M, Jørgensen CI, Svendsen A, De Schryver FC, Hofkens J, Uji-i H. Rocha S, et al. Among authors: svendsen a. Chemphyschem. 2009 Jan 12;10(1):151-61. doi: 10.1002/cphc.200800537. Chemphyschem. 2009. PMID: 19058276 Free article.

7

Enzymatic activity of lipase-nanoparticle conjugates and the digestion of lipid liquid crystalline assemblies.

Brennan JL, Kanaras AG, Nativo P, Tshikhudo TR, Rees C, Fernandez LC, Dirvianskyte N, Razumas V, Skjøt M, Svendsen A, Jørgensen CI, Schweins R, Zackrisson M, Nylander T, Brust M, Barauskas J. Brennan JL, et al. Among authors: svendsen a. Langmuir. 2010 Aug 17;26(16):13590-9. doi: 10.1021/la1018604. Langmuir. 2010. PMID: 20695608

8

The Enzymatic Activity of Lipases Correlates with Polarity-Induced Conformational Changes: A Trp-Induced Quenching Fluorescence Study.

Skjold-Jørgensen J, Bhatia VK, Vind J, Svendsen A, Bjerrum MJ, Farrens D. Skjold-Jørgensen J, et al. Among authors: svendsen a. Biochemistry. 2015 Jul 14;54(27):4186-96. doi: 10.1021/acs.biochem.5b00328. Epub 2015 Jul 1. Biochemistry. 2015. PMID: 26087334

9

Lipases That Activate at High Solvent Polarities.

Skjold-Jørgensen J, Vind J, Svendsen A, Bjerrum MJ. Skjold-Jørgensen J, et al. Among authors: svendsen a. Biochemistry. 2016 Jan 12;55(1):146-56. doi: 10.1021/acs.biochem.5b01114. Epub 2015 Dec 22. Biochemistry. 2016. PMID: 26645098

10

Altering the activation mechanism in Thermomyces lanuginosus lipase.

Skjold-Jørgensen J, Vind J, Svendsen A, Bjerrum MJ. Skjold-Jørgensen J, et al. Among authors: svendsen a. Biochemistry. 2014 Jul 1;53(25):4152-60. doi: 10.1021/bi500233h. Epub 2014 Jun 16. Biochemistry. 2014. PMID: 24870718

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