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Clopidogrel: a case for indication-specific pharmacogenetics.
Johnson JA, Roden DM, Lesko LJ, Ashley E, Klein TE, Shuldiner AR. Johnson JA, et al. Among authors: lesko lj. Clin Pharmacol Ther. 2012 May;91(5):774-6. doi: 10.1038/clpt.2012.21. Clin Pharmacol Ther. 2012. PMID: 22513313 Free PMC article.
The Pharmacogenomics Research Network Translational Pharmacogenetics Program: overcoming challenges of real-world implementation.
Shuldiner AR, Relling MV, Peterson JF, Hicks JK, Freimuth RR, Sadee W, Pereira NL, Roden DM, Johnson JA, Klein TE; Pharmacogenomics Research Network Translational Pharmacogenetics Program Group; Shuldiner AR, Vesely M, Robinson SW, Ambulos N Jr, Stass SA, Kelemen MD, Brown LA, Pollin TI, Beitelshees AL, Zhao RY, Pakyz RE, Palmer K, Alestock T, O'Neill C, Maloney K, Branham A, Sewell D, Relling MV, Crews K, Hoffman J, Cross S, Haidar C, Baker D, Hicks JK, Bell G, Greeson F, Gaur A, Reiss U, Huettel A, Cheng C, Gajjar A, Pappo A, Howard S, Hudson M, Pui CH, Jeha S, Evans WE, Broeckel U, Altman RB, Gong L, Whirl-Carrillo M, Klein TE, Sadee W, Manickam K, Sweet KM, Embi PJ, Roden D, Peterson J, Denny J, Schildcrout J, Bowton E, Pulley J, Beller M, Mitchell J, Danciu I, Price L, Pereira NL, Weinshilboum R, Wang L, Johnson JA, Nelson D, Clare-Salzler M, Elsey A, Burkley B, Langaee T, Liu F, Nessl D, Dong HJ, Lesko L, Freimuth RR, Chute CG. Shuldiner AR, et al. Clin Pharmacol Ther. 2013 Aug;94(2):207-10. doi: 10.1038/clpt.2013.59. Epub 2013 Mar 19. Clin Pharmacol Ther. 2013. PMID: 23588301 Free PMC article.
Development of a physiology-directed population pharmacokinetic and pharmacodynamic model for characterizing the impact of genetic and demographic factors on clopidogrel response in healthy adults.
Jiang XL, Samant S, Lewis JP, Horenstein RB, Shuldiner AR, Yerges-Armstrong LM, Peletier LA, Lesko LJ, Schmidt S. Jiang XL, et al. Among authors: lesko lj. Eur J Pharm Sci. 2016 Jan 20;82:64-78. doi: 10.1016/j.ejps.2015.10.024. Epub 2015 Oct 30. Eur J Pharm Sci. 2016. PMID: 26524713 Free PMC article. Clinical Trial.
Clinical pharmacokinetics and pharmacodynamics of clopidogrel.
Jiang XL, Samant S, Lesko LJ, Schmidt S. Jiang XL, et al. Among authors: lesko lj. Clin Pharmacokinet. 2015 Feb;54(2):147-66. doi: 10.1007/s40262-014-0230-6. Clin Pharmacokinet. 2015. PMID: 25559342 Free PMC article. Review.
Systems approaches in risk assessment.
Lesko LJ, Zheng S, Schmidt S. Lesko LJ, et al. Clin Pharmacol Ther. 2013 May;93(5):413-24. doi: 10.1038/clpt.2013.29. Epub 2013 Feb 11. Clin Pharmacol Ther. 2013. PMID: 23531724
218 results