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PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8.
Smith VE, Read ML, Turnell AS, Sharma N, Lewy GD, Fong JC, Seed RI, Kwan P, Ryan G, Mehanna H, Chan SY, Darras VM, Boelaert K, Franklyn JA, McCabe CJ. Smith VE, et al. Among authors: turnell as. Endocrinology. 2012 Jul;153(7):3526-36. doi: 10.1210/en.2011-2030. Epub 2012 Apr 25. Endocrinology. 2012. PMID: 22535767
The PTTG1-binding factor (PBF/PTTG1IP) regulates p53 activity in thyroid cells.
Read ML, Seed RI, Fong JC, Modasia B, Ryan GA, Watkins RJ, Gagliano T, Smith VE, Stratford AL, Kwan PK, Sharma N, Dixon OM, Watkinson JC, Boelaert K, Franklyn JA, Turnell AS, McCabe CJ. Read ML, et al. Among authors: turnell as. Endocrinology. 2014 Apr;155(4):1222-34. doi: 10.1210/en.2013-1646. Epub 2014 Feb 7. Endocrinology. 2014. PMID: 24506068 Free PMC article.
Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer.
Read ML, Fong JC, Modasia B, Fletcher A, Imruetaicharoenchoke W, Thompson RJ, Nieto H, Reynolds JJ, Bacon A, Mallick U, Hackshaw A, Watkinson JC, Boelaert K, Turnell AS, Smith VE, McCabe CJ. Read ML, et al. Among authors: turnell as. Oncogene. 2017 Sep 14;36(37):5296-5308. doi: 10.1038/onc.2017.154. Epub 2017 May 15. Oncogene. 2017. PMID: 28504713 Free PMC article.
PTTG and PBF Functionally Interact with p53 and Predict Overall Survival in Head and Neck Cancer.
Read ML, Modasia B, Fletcher A, Thompson RJ, Brookes K, Rae PC, Nieto HR, Poole VL, Roberts S, Campbell MJ, Boelaert K, Turnell AS, Smith VE, Mehanna H, McCabe CJ. Read ML, et al. Among authors: turnell as. Cancer Res. 2018 Oct 15;78(20):5863-5876. doi: 10.1158/0008-5472.CAN-18-0855. Epub 2018 Aug 28. Cancer Res. 2018. PMID: 30154144 Free PMC article.
Targeting Novel Sodium Iodide Symporter Interactors ADP-Ribosylation Factor 4 and Valosin-Containing Protein Enhances Radioiodine Uptake.
Fletcher A, Read ML, Thornton CEM, Larner DP, Poole VL, Brookes K, Nieto HR, Alshahrani M, Thompson RJ, Lavery GG, Landa I, Fagin JA, Campbell MJ, Boelaert K, Turnell AS, Smith VE, McCabe CJ. Fletcher A, et al. Among authors: turnell as. Cancer Res. 2020 Jan 1;80(1):102-115. doi: 10.1158/0008-5472.CAN-19-1957. Epub 2019 Oct 31. Cancer Res. 2020. PMID: 31672844 Free PMC article.
51 results