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994 results

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Page 1
A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation.
Bergamini G, Bell K, Shimamura S, Werner T, Cansfield A, Müller K, Perrin J, Rau C, Ellard K, Hopf C, Doce C, Leggate D, Mangano R, Mathieson T, O'Mahony A, Plavec I, Rharbaoui F, Reinhard F, Savitski MM, Ramsden N, Hirsch E, Drewes G, Rausch O, Bantscheff M, Neubauer G. Bergamini G, et al. Among authors: perrin j. Nat Chem Biol. 2012 Apr 29;8(6):576-82. doi: 10.1038/nchembio.957. Nat Chem Biol. 2012. PMID: 22544264
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors.
Bantscheff M, Eberhard D, Abraham Y, Bastuck S, Boesche M, Hobson S, Mathieson T, Perrin J, Raida M, Rau C, Reader V, Sweetman G, Bauer A, Bouwmeester T, Hopf C, Kruse U, Neubauer G, Ramsden N, Rick J, Kuster B, Drewes G. Bantscheff M, et al. Among authors: perrin j. Nat Biotechnol. 2007 Sep;25(9):1035-44. doi: 10.1038/nbt1328. Epub 2007 Aug 26. Nat Biotechnol. 2007. PMID: 17721511
Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors.
Klaeger S, Gohlke B, Perrin J, Gupta V, Heinzlmeir S, Helm D, Qiao H, Bergamini G, Handa H, Savitski MM, Bantscheff M, Médard G, Preissner R, Kuster B. Klaeger S, et al. Among authors: perrin j. ACS Chem Biol. 2016 May 20;11(5):1245-54. doi: 10.1021/acschembio.5b01063. Epub 2016 Feb 25. ACS Chem Biol. 2016. PMID: 26863403
Identifying drug targets in tissues and whole blood with thermal-shift profiling.
Perrin J, Werner T, Kurzawa N, Rutkowska A, Childs DD, Kalxdorf M, Poeckel D, Stonehouse E, Strohmer K, Heller B, Thomson DW, Krause J, Becher I, Eberl HC, Vappiani J, Sevin DC, Rau CE, Franken H, Huber W, Faelth-Savitski M, Savitski MM, Bantscheff M, Bergamini G. Perrin J, et al. Nat Biotechnol. 2020 Mar;38(3):303-308. doi: 10.1038/s41587-019-0388-4. Epub 2020 Jan 20. Nat Biotechnol. 2020. PMID: 31959954
Drug Target Identification in Tissues by Thermal Proteome Profiling.
Mateus A, Kurzawa N, Perrin J, Bergamini G, Savitski MM. Mateus A, et al. Among authors: perrin j. Annu Rev Pharmacol Toxicol. 2022 Jan 6;62:465-482. doi: 10.1146/annurev-pharmtox-052120-013205. Epub 2021 Sep 9. Annu Rev Pharmacol Toxicol. 2022. PMID: 34499524 Review.
Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor.
Thomson DW, Poeckel D, Zinn N, Rau C, Strohmer K, Wagner AJ, Graves AP, Perrin J, Bantscheff M, Duempelfeld B, Kasparcova V, Ramanjulu JM, Pesiridis GS, Muelbaier M, Bergamini G. Thomson DW, et al. Among authors: perrin j. ACS Med Chem Lett. 2019 Mar 11;10(5):780-785. doi: 10.1021/acsmedchemlett.9b00027. eCollection 2019 May 9. ACS Med Chem Lett. 2019. PMID: 31097999 Free PMC article.
"ALKanthocytes".
Marchand K, Perrin J. Marchand K, et al. Among authors: perrin j. Ann Biol Clin (Paris). 2025 Jan 3;82(6):0. doi: 10.1684/abc.2024.1929. Online ahead of print. Ann Biol Clin (Paris). 2025. PMID: 39754361 No abstract available.
994 results