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Anti-retroviral therapy with protease inhibitors decreases virulence enzyme expression in vivo by Candida albicans without selection of avirulent fungus strains or decreasing their anti-mycotic susceptibility.
De Bernardis F, Tacconelli E, Mondello F, Cataldo A, Arancia S, Cauda R, Cassone A. De Bernardis F, et al. FEMS Immunol Med Microbiol. 2004 May 1;41(1):27-34. doi: 10.1016/j.femsim.2003.12.006. FEMS Immunol Med Microbiol. 2004. PMID: 15094164 Free article. Clinical Trial.
Evaluation of efficacy, pharmacokinetics and tolerability of peptidomimetic aspartic proteinase inhibitors as cream formulation in experimental vaginal candidiasis.
De Bernardis F, Arancia S, Tringali G, Greco MC, Ragazzoni E, Calugi C, Trabocchi A, Sandini S, Graziani S, Cauda R, Cassone A, Guarna A, Navarra P. De Bernardis F, et al. J Pharm Pharmacol. 2014 Aug;66(8):1094-101. doi: 10.1111/jphp.12240. Epub 2014 Mar 13. J Pharm Pharmacol. 2014. PMID: 24628362
133 results