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Inhibition of EP4 signaling attenuates aortic aneurysm formation.
Yokoyama U, Ishiwata R, Jin MH, Kato Y, Suzuki O, Jin H, Ichikawa Y, Kumagaya S, Katayama Y, Fujita T, Okumura S, Sato M, Sugimoto Y, Aoki H, Suzuki S, Masuda M, Minamisawa S, Ishikawa Y. Yokoyama U, et al. Among authors: ishikawa y. PLoS One. 2012;7(5):e36724. doi: 10.1371/journal.pone.0036724. Epub 2012 May 3. PLoS One. 2012. PMID: 22570740 Free PMC article.
The prostanoid EP4 receptor and its signaling pathway.
Yokoyama U, Iwatsubo K, Umemura M, Fujita T, Ishikawa Y. Yokoyama U, et al. Among authors: ishikawa y. Pharmacol Rev. 2013 Jun 17;65(3):1010-52. doi: 10.1124/pr.112.007195. Print 2013 Jul. Pharmacol Rev. 2013. PMID: 23776144 Review.
Excessive EP4 Signaling in Smooth Muscle Cells Induces Abdominal Aortic Aneurysm by Amplifying Inflammation.
Hiromi T, Yokoyama U, Kurotaki D, Mamun A, Ishiwata R, Ichikawa Y, Nishihara H, Umemura M, Fujita T, Yasuda S, Minami T, Goda M, Uchida K, Suzuki S, Takeuchi I, Masuda M, Breyer RM, Tamura T, Ishikawa Y. Hiromi T, et al. Among authors: ishikawa y. Arterioscler Thromb Vasc Biol. 2020 Jun;40(6):1559-1573. doi: 10.1161/ATVBAHA.120.314297. Epub 2020 Apr 23. Arterioscler Thromb Vasc Biol. 2020. PMID: 32321307 Free PMC article.
Prostaglandin E2-activated Epac promotes neointimal formation of the rat ductus arteriosus by a process distinct from that of cAMP-dependent protein kinase A.
Yokoyama U, Minamisawa S, Quan H, Akaike T, Suzuki S, Jin M, Jiao Q, Watanabe M, Otsu K, Iwasaki S, Nishimaki S, Sato M, Ishikawa Y. Yokoyama U, et al. Among authors: ishikawa y. J Biol Chem. 2008 Oct 17;283(42):28702-9. doi: 10.1074/jbc.M804223200. Epub 2008 Aug 11. J Biol Chem. 2008. PMID: 18697745 Free PMC article.
3,770 results