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106 results

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The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia.
Toscan CE, McCalmont H, Ashoorzadeh A, Lin X, Fu Z, Doculara L, Kosasih HJ, Cadiz R, Zhou A, Williams S, Evans K, Khalili F, Cai R, Yeats KL, Gifford AJ, Pickford R, Mayoh C, Xie J, Henderson MJ, Trahair TN, Patterson AV, Smaill JB, de Bock CE, Lock RB. Toscan CE, et al. Among authors: patterson av. Blood Cancer J. 2024 Nov 6;14(1):192. doi: 10.1038/s41408-024-01180-x. Blood Cancer J. 2024. PMID: 39505850 Free PMC article.
Discovery of 6-Formylpyridyl Urea Derivatives as Potent Reversible-Covalent Fibroblast Growth Factor Receptor 4 Inhibitors with Improved Anti-Hepatocellular Carcinoma Activity.
Yang F, Lin Q, Song X, Huang H, Chen X, Tan J, Li Y, Zhou Y, Tu Z, Du H, Zhang ZM, Ortega R, Lin X, Patterson AV, Smaill JB, Chen Y, Lu X. Yang F, et al. Among authors: patterson av. J Med Chem. 2024 Feb 22;67(4):2667-2689. doi: 10.1021/acs.jmedchem.3c01810. Epub 2024 Feb 13. J Med Chem. 2024. PMID: 38348819
Tumor-targeting bacteria as immune stimulants - the future of cancer immunotherapy?
Mowday AM, van de Laak JM, Fu Z, Henare KL, Dubois L, Lambin P, Theys J, Patterson AV. Mowday AM, et al. Among authors: patterson av. Crit Rev Microbiol. 2024 Nov;50(6):955-970. doi: 10.1080/1040841X.2024.2311653. Epub 2024 Feb 12. Crit Rev Microbiol. 2024. PMID: 38346140 Free PMC article. Review.
106 results