Upton P - Search Results

1

Large scale biobanking of blood - the importance of high density sample processing procedures.

Malm J, Végvári A, Rezeli M, Upton P, Danmyr P, Nilsson R, Steinfelder E, Marko-Varga G. Malm J, et al. Among authors: upton p. J Proteomics. 2012 Dec 5;76 Spec No.:116-24. doi: 10.1016/j.jprot.2012.05.003. Epub 2012 May 9. J Proteomics. 2012. PMID: 22580359 Clinical Trial.

2

Standardization developments for large scale biobanks in smoking related diseases - a model system for blood sample processing and storage.

Malm J, Fehniger TE, Danmyr P, Végvári Á, Welinder C, Lindberg H, Upton P, Carter S, Appelqvist R, Sjödin K, Wieslander E, Dahlbäck M, Rezeli M, Erlinge D, Marko-Varga G. Malm J, et al. Among authors: upton p. Transl Respir Med. 2013 Dec;1(1):14. doi: 10.1186/2213-0802-1-14. Epub 2013 Aug 30. Transl Respir Med. 2013. PMID: 27234395 Free PMC article.

3

Transforming growth factor-β(1) represses bone morphogenetic protein-mediated Smad signaling in pulmonary artery smooth muscle cells via Smad3.

Upton PD, Davies RJ, Tajsic T, Morrell NW. Upton PD, et al. Am J Respir Cell Mol Biol. 2013 Dec;49(6):1135-45. doi: 10.1165/rcmb.2012-0470OC. Am J Respir Cell Mol Biol. 2013. PMID: 23937428 Free PMC article.

4

Bone morphogenetic protein receptor type II deficiency and increased inflammatory cytokine production. A gateway to pulmonary arterial hypertension.

Soon E, Crosby A, Southwood M, Yang P, Tajsic T, Toshner M, Appleby S, Shanahan CM, Bloch KD, Pepke-Zaba J, Upton P, Morrell NW. Soon E, et al. Among authors: upton p. Am J Respir Crit Care Med. 2015 Oct 1;192(7):859-72. doi: 10.1164/rccm.201408-1509OC. Am J Respir Crit Care Med. 2015. PMID: 26073741 Free PMC article.

5

Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor.

Atkinson C, Stewart S, Upton PD, Machado R, Thomson JR, Trembath RC, Morrell NW. Atkinson C, et al. Circulation. 2002 Apr 9;105(14):1672-8. doi: 10.1161/01.cir.0000012754.72951.3d. Circulation. 2002. PMID: 11940546

6

Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension.

Rudarakanchana N, Flanagan JA, Chen H, Upton PD, Machado R, Patel D, Trembath RC, Morrell NW. Rudarakanchana N, et al. Hum Mol Genet. 2002 Jun 15;11(13):1517-25. doi: 10.1093/hmg/11.13.1517. Hum Mol Genet. 2002. PMID: 12045205

7

Hypoxic induction of cox-2 regulates proliferation of human pulmonary artery smooth muscle cells.

Yang X, Sheares KK, Davie N, Upton PD, Taylor GW, Horsley J, Wharton J, Morrell NW. Yang X, et al. Am J Respir Cell Mol Biol. 2002 Dec;27(6):688-96. doi: 10.1165/rcmb.2002-0067OC. Am J Respir Cell Mol Biol. 2002. PMID: 12444028

8

Mechanism of cicaprost-induced desensitization in rat pulmonary artery smooth muscle cells involves a PKA-mediated inhibition of adenylyl cyclase.

Sobolewski A, Jourdan KB, Upton PD, Long L, Morrell NW. Sobolewski A, et al. Am J Physiol Lung Cell Mol Physiol. 2004 Aug;287(2):L352-9. doi: 10.1152/ajplung.00270.2003. Epub 2004 Apr 23. Am J Physiol Lung Cell Mol Physiol. 2004. PMID: 15107293 Free article.

9

BMP4 inhibits proliferation and promotes myocyte differentiation of lung fibroblasts via Smad1 and JNK pathways.

Jeffery TK, Upton PD, Trembath RC, Morrell NW. Jeffery TK, et al. Am J Physiol Lung Cell Mol Physiol. 2005 Feb;288(2):L370-8. doi: 10.1152/ajplung.00242.2004. Epub 2004 Oct 29. Am J Physiol Lung Cell Mol Physiol. 2005. PMID: 15516492 Free article.

10

Dysfunctional Smad signaling contributes to abnormal smooth muscle cell proliferation in familial pulmonary arterial hypertension.

Yang X, Long L, Southwood M, Rudarakanchana N, Upton PD, Jeffery TK, Atkinson C, Chen H, Trembath RC, Morrell NW. Yang X, et al. Circ Res. 2005 May 27;96(10):1053-63. doi: 10.1161/01.RES.0000166926.54293.68. Epub 2005 Apr 21. Circ Res. 2005. PMID: 15845886

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