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Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail.
Kim HJ, Litzenburger BC, Cui X, Delgado DA, Grabiner BC, Lin X, Lewis MT, Gottardis MM, Wong TW, Attar RM, Carboni JM, Lee AV. Kim HJ, et al. Among authors: lewis mt. Mol Cell Biol. 2007 Apr;27(8):3165-75. doi: 10.1128/MCB.01315-06. Epub 2007 Feb 12. Mol Cell Biol. 2007. PMID: 17296734 Free PMC article.
Separation by cell size enriches for mammary stem cell repopulation activity.
Machado HL, Kittrell FS, Edwards D, White AN, Atkinson RL, Rosen JM, Medina D, Lewis MT. Machado HL, et al. Among authors: lewis mt. Stem Cells Transl Med. 2013 Mar;2(3):199-203. doi: 10.5966/sctm.2012-0121. Epub 2013 Feb 13. Stem Cells Transl Med. 2013. PMID: 23408103 Free PMC article.
188 results