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Human studies of angiogenic gene therapy.
Gupta R, Tongers J, Losordo DW. Gupta R, et al. Circ Res. 2009 Oct 9;105(8):724-36. doi: 10.1161/CIRCRESAHA.109.200386. Circ Res. 2009. PMID: 19815827 Free PMC article. Review.
Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB.
Verma SK, Krishnamurthy P, Barefield D, Singh N, Gupta R, Lambers E, Thal M, Mackie A, Hoxha E, Ramirez V, Qin G, Sadayappan S, Ghosh AK, Kishore R. Verma SK, et al. Among authors: gupta r. Circulation. 2012 Jul 24;126(4):418-29. doi: 10.1161/CIRCULATIONAHA.112.112185. Epub 2012 Jun 15. Circulation. 2012. PMID: 22705886 Free PMC article.
The angiogenic factor secretoneurin induces coronary angiogenesis in a model of myocardial infarction by stimulation of vascular endothelial growth factor signaling in endothelial cells.
Albrecht-Schgoer K, Schgoer W, Holfeld J, Theurl M, Wiedemann D, Steger C, Gupta R, Semsroth S, Fischer-Colbrie R, Beer AG, Stanzl U, Huber E, Misener S, Dejaco D, Kishore R, Pachinger O, Grimm M, Bonaros N, Kirchmair R. Albrecht-Schgoer K, et al. Among authors: gupta r. Circulation. 2012 Nov 20;126(21):2491-501. doi: 10.1161/CIRCULATIONAHA.111.076950. Epub 2012 Oct 18. Circulation. 2012. PMID: 23081990 Free PMC article.
Restrictive Versus Liberal Transfusion in Patients With Type 1 or Type 2 Myocardial Infarction: A Prespecified Analysis of the MINT Trial.
DeFilippis AP, Abbott JD, Herbert BM, Bertolet MH, Chaitman BR, White HD, Goldsweig AM, Polonsky TS, Gupta R, Alsweiler C, Silvain J, de Barros E Silva PGM, Hillis GS, Daneault B, Tessalee M, Menegus MA, Rao SV, Lopes RD, Hébert PC, Alexander JH, Brooks MM, Carson JL, Goodman SG; MINT Investigators. DeFilippis AP, et al. Among authors: gupta r. Circulation. 2024 Dec 3;150(23):1826-1836. doi: 10.1161/CIRCULATIONAHA.124.071208. Epub 2024 Aug 29. Circulation. 2024. PMID: 39206549 Clinical Trial.
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