Smeets J - Search Results

1

Physiologically based pharmacokinetic modeling to investigate regional brain distribution kinetics in rats.

Westerhout J, Ploeger B, Smeets J, Danhof M, de Lange EC. Westerhout J, et al. Among authors: smeets j. AAPS J. 2012 Sep;14(3):543-53. doi: 10.1208/s12248-012-9366-1. Epub 2012 May 17. AAPS J. 2012. PMID: 22588644 Free PMC article. Review.

2

The impact of P-gp functionality on non-steady state relationships between CSF and brain extracellular fluid.

Westerhout J, Smeets J, Danhof M, de Lange EC. Westerhout J, et al. Among authors: smeets j. J Pharmacokinet Pharmacodyn. 2013 Jun;40(3):327-42. doi: 10.1007/s10928-013-9314-4. Epub 2013 Mar 29. J Pharmacokinet Pharmacodyn. 2013. PMID: 23539188 Free PMC article.

3

Pharmacokinetic-pharmacodynamic model for the reversal of neuromuscular blockade by sugammadex.

Ploeger BA, Smeets J, Strougo A, Drenth HJ, Ruigt G, Houwing N, Danhof M. Ploeger BA, et al. Among authors: smeets j. Anesthesiology. 2009 Jan;110(1):95-105. doi: 10.1097/ALN.0b013e318190bc32. Anesthesiology. 2009. PMID: 19104176

4

Pharmacokinetics of a granisetron transdermal system for the treatment of chemotherapy-induced nausea and vomiting.

Howell J, Smeets J, Drenth HJ, Gill D. Howell J, et al. Among authors: smeets j. J Oncol Pharm Pract. 2009 Dec;15(4):223-31. doi: 10.1177/1078155209104063. J Oncol Pharm Pract. 2009. PMID: 19304880 Clinical Trial.

5

Assessment of the potential for displacement interactions with sugammadex: a pharmacokinetic-pharmacodynamic modelling approach.

Zwiers A, van den Heuvel M, Smeets J, Rutherford S. Zwiers A, et al. Among authors: smeets j. Clin Drug Investig. 2011;31(2):101-11. doi: 10.2165/11584730-000000000-00000. Clin Drug Investig. 2011. PMID: 21067251

6

Sugammadex is cleared rapidly and primarily unchanged via renal excretion.

Peeters P, Passier P, Smeets J, Zwiers A, de Zwart M, van de Wetering-Krebbers S, van Iersel M, van Marle S, van den Dobbelsteen D. Peeters P, et al. Among authors: smeets j. Biopharm Drug Dispos. 2011 Apr;32(3):159-67. doi: 10.1002/bdd.747. Epub 2011 Mar 1. Biopharm Drug Dispos. 2011. PMID: 21370235

7

Safety, tolerability and pharmacokinetics of sugammadex using single high doses (up to 96 mg/kg) in healthy adult subjects: a randomized, double-blind, crossover, placebo-controlled, single-centre study.

Peeters PA, van den Heuvel MW, van Heumen E, Passier PC, Smeets JM, van Iersel T, Zwiers A. Peeters PA, et al. Clin Drug Investig. 2010;30(12):867-74. doi: 10.1007/BF03256915. Clin Drug Investig. 2010. PMID: 20825252 Clinical Trial.

8

Safety and tolerability of single intravenous doses of sugammadex administered simultaneously with rocuronium or vecuronium in healthy volunteers.

Cammu G, De Kam PJ, Demeyer I, Decoopman M, Peeters PA, Smeets JM, Foubert L. Cammu G, et al. Among authors: smeets jm. Br J Anaesth. 2008 Mar;100(3):373-9. doi: 10.1093/bja/aem402. Epub 2008 Jan 31. Br J Anaesth. 2008. PMID: 18238834 Free article. Clinical Trial.

9

Sugammadex is not associated with QT/QTc prolongation: methodology aspects of an intravenous moxifloxacin-controlled thorough QT study.

de Kam PJ, van Kuijk J, Smeets J, Thomsen T, Peeters P. de Kam PJ, et al. Among authors: smeets j. Int J Clin Pharmacol Ther. 2012 Aug;50(8):595-604. doi: 10.5414/CP201693. Int J Clin Pharmacol Ther. 2012. PMID: 22735462 Clinical Trial.

10

Pharmacokinetic evaluation of three different intramuscular doses of nandrolone decanoate: analysis of serum and urine samples in healthy men.

Bagchus WM, Smeets JM, Verheul HA, De Jager-Van Der Veen SM, Port A, Geurts TB. Bagchus WM, et al. J Clin Endocrinol Metab. 2005 May;90(5):2624-30. doi: 10.1210/jc.2004-1526. Epub 2005 Feb 15. J Clin Endocrinol Metab. 2005. PMID: 15713722

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