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Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes.
McCoull W, Addie MS, Birch AM, Birtles S, Buckett LK, Butlin RJ, Bowker SS, Boyd S, Chapman S, Davies RD, Donald CS, Green CP, Jenner C, Kemmitt PD, Leach AG, Moody GC, Gutierrez PM, Newcombe NJ, Nowak T, Packer MJ, Plowright AT, Revill J, Schofield P, Sheldon C, Stokes S, Turnbull AV, Wang SJ, Whalley DP, Wood JM. McCoull W, et al. Among authors: chapman s. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3873-8. doi: 10.1016/j.bmcl.2012.04.117. Epub 2012 May 2. Bioorg Med Chem Lett. 2012. PMID: 22608962
Discovery and optimization of a series of carbazole ureas as NPY5 antagonists for the treatment of obesity.
Block MH, Boyer S, Brailsford W, Brittain DR, Carroll D, Chapman S, Clarke DS, Donald CS, Foote KM, Godfrey L, Ladner A, Marsham PR, Masters DJ, Mee CD, O'Donovan MR, Pease JE, Pickup AG, Rayner JW, Roberts A, Schofield P, Suleman A, Turnbull AV. Block MH, et al. Among authors: chapman s. J Med Chem. 2002 Aug 1;45(16):3509-23. doi: 10.1021/jm011125x. J Med Chem. 2002. PMID: 12139462
Phenoxypropylamines: a new series of squalene synthase inhibitors.
Brown GR, Butlin RJ, Chapman S, Eakin MA, Foubister AJ, Freeman S, Griffiths D, Harrison PJ, Johnson MC, Mallion KB, et al. Brown GR, et al. Among authors: chapman s. J Med Chem. 1995 Oct 13;38(21):4157-60. doi: 10.1021/jm00021a003. J Med Chem. 1995. PMID: 7473541 No abstract available.
Making medicinal chemistry more effective--application of Lean Sigma to improve processes, speed and quality.
Andersson S, Armstrong A, Björe A, Bowker S, Chapman S, Davies R, Donald C, Egner B, Elebring T, Holmqvist S, Inghardt T, Johannesson P, Johansson M, Johnstone C, Kemmitt P, Kihlberg J, Korsgren P, Lemurell M, Moore J, Pettersson JA, Pointon H, Pontén F, Schofield P, Selmi N, Whittamore P. Andersson S, et al. Among authors: chapman s. Drug Discov Today. 2009 Jun;14(11-12):598-604. doi: 10.1016/j.drudis.2009.03.005. Epub 2009 Mar 11. Drug Discov Today. 2009. PMID: 19508922 Review.
Whole genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia.
Li R, Taliun SAG, Liao K, Flickinger M, Sobell JL, Genovese G, Locke AE, Chiu RR, LeFaive J, Martins T, Chapman S, Neumann A, Handsaker RE, Arnett DK, Barnes KC, Boerwinkle E, Braff D, Cade BE, Fornage M, Gibbs RA, Hoth KF, Hou L, Kooperberg C, Loos RJF, Metcalf GA, Montgomery CG, Morrison AC, Qin ZS, Redline S, Reiner AP, Rich SS, Rotter JI, Taylor KD, Viaud-Martinez KA; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Genomic Psychiatry Cohort investigators; Bigdeli TB, Gabriel S, Zollner S, Smith AV, Abecasis G, McCarroll S, Pato MT, Pato CN, Boehnke M, Knowles J, Kang HM, Ophoff RA, Ernst J, Scott LJ. Li R, et al. Among authors: chapman s. medRxiv [Preprint]. 2024 Dec 29:2024.12.27.24319111. doi: 10.1101/2024.12.27.24319111. medRxiv. 2024. PMID: 39763555 Free PMC article. Preprint.
Dexterity assessment of hospital workers: prospective comparative study.
Joseph T, Brown OI, Khalid S, Giannoudi M, Sagar RC, Bunola-Hadfield E, Chapman SJ, A Slater T, Straw S, Drozd M. Joseph T, et al. Among authors: chapman sj. BMJ. 2024 Dec 20;387:e081814. doi: 10.1136/bmj-2024-081814. BMJ. 2024. PMID: 39706594 Free article.
2,467 results