Engst W - Search Results

1

Metabolism of methyleugenol in liver microsomes and primary hepatocytes: pattern of metabolites, cytotoxicity, and DNA-adduct formation.

Cartus AT, Herrmann K, Weishaupt LW, Merz KH, Engst W, Glatt H, Schrenk D. Cartus AT, et al. Among authors: engst w. Toxicol Sci. 2012 Sep;129(1):21-34. doi: 10.1093/toxsci/kfs181. Epub 2012 May 18. Toxicol Sci. 2012. PMID: 22610610

2

Benzylic hydroxylation of 1-methylpyrene and 1-ethylpyrene by human and rat cytochromes P450 individually expressed in V79 Chinese hamster cells.

Engst W, Landsiedel R, Hermersdörfer H, Doehmer J, Glatt H. Engst W, et al. Carcinogenesis. 1999 Sep;20(9):1777-85. doi: 10.1093/carcin/20.9.1777. Carcinogenesis. 1999. PMID: 10469624

3

Directing role of organic anion transporters in the excretion of mercapturic acids of alkylated polycyclic aromatic hydrocarbons.

Bakhiya N, Batke M, Laake J, Monien BH, Frank H, Seidel A, Engst W, Glatt H. Bakhiya N, et al. Among authors: engst w. Drug Metab Dispos. 2007 Oct;35(10):1824-31. doi: 10.1124/dmd.107.016964. Epub 2007 Jul 16. Drug Metab Dispos. 2007. PMID: 17639024

4

Time course of hepatic 1-methylpyrene DNA adducts in rats determined by isotope dilution LC-MS/MS and 32P-postlabeling.

Monien BH, Müller C, Engst W, Frank H, Seidel A, Glatt H. Monien BH, et al. Among authors: engst w. Chem Res Toxicol. 2008 Oct;21(10):2017-25. doi: 10.1021/tx800217d. Epub 2008 Sep 13. Chem Res Toxicol. 2008. PMID: 18788758

5

1-Methoxy-3-indolylmethyl glucosinolate; a potent genotoxicant in bacterial and mammalian cells: Mechanisms of bioactivation.

Glatt H, Baasanjav-Gerber C, Schumacher F, Monien BH, Schreiner M, Frank H, Seidel A, Engst W. Glatt H, et al. Among authors: engst w. Chem Biol Interact. 2011 Jun 30;192(1-2):81-6. doi: 10.1016/j.cbi.2010.09.009. Epub 2010 Sep 21. Chem Biol Interact. 2011. PMID: 20846518

6

Conjugation of 4-nitrophenol and 4-hydroxylonazolac in V79-derived cells expressing individual forms of human sulphotransferases.

Engst W, Pabel U, Glatt H. Engst W, et al. Environ Toxicol Pharmacol. 2002 Jul;11(3-4):243-50. doi: 10.1016/s1382-6689(02)00022-4. Environ Toxicol Pharmacol. 2002. PMID: 21782608

7

Identification of human and murine sulfotransferases able to activate hydroxylated metabolites of methyleugenol to mutagens in Salmonella typhimurium and detection of associated DNA adducts using UPLC-MS/MS methods.

Herrmann K, Engst W, Appel KE, Monien BH, Glatt H. Herrmann K, et al. Among authors: engst w. Mutagenesis. 2012 Jul;27(4):453-62. doi: 10.1093/mutage/ges004. Epub 2012 Feb 15. Mutagenesis. 2012. PMID: 22337896

8

Mutagenicity of 5-hydroxymethylfurfural in V79 cells expressing human SULT1A1: identification and mass spectrometric quantification of DNA adducts formed.

Monien BH, Engst W, Barknowitz G, Seidel A, Glatt H. Monien BH, et al. Among authors: engst w. Chem Res Toxicol. 2012 Jul 16;25(7):1484-92. doi: 10.1021/tx300150n. Epub 2012 May 15. Chem Res Toxicol. 2012. PMID: 22563731

9

Detection of DNA adducts originating from 1-methoxy-3-indolylmethyl glucosinolate using isotope-dilution UPLC-ESI-MS/MS.

Schumacher F, Engst W, Monien BH, Florian S, Schnapper A, Steinhauser L, Albert K, Frank H, Seidel A, Glatt H. Schumacher F, et al. Among authors: engst w. Anal Chem. 2012 Jul 17;84(14):6256-62. doi: 10.1021/ac301436q. Epub 2012 Jul 3. Anal Chem. 2012. PMID: 22816785

10

Optimized enzymatic hydrolysis of DNA for LC-MS/MS analyses of adducts of 1-methoxy-3-indolylmethyl glucosinolate and methyleugenol.

Schumacher F, Herrmann K, Florian S, Engst W, Glatt H. Schumacher F, et al. Among authors: engst w. Anal Biochem. 2013 Mar 1;434(1):4-11. doi: 10.1016/j.ab.2012.11.001. Epub 2012 Nov 9. Anal Biochem. 2013. PMID: 23142629

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