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Let's (P-s)talk about specialized ribosomes.
Harvey RF, Pöyry T, Willis AE. Harvey RF, et al. Among authors: poyry t. Mol Cell. 2024 Dec 5;84(23):4478-4479. doi: 10.1016/j.molcel.2024.11.011. Mol Cell. 2024. PMID: 39642853
Eukaryotic initiation factor 4B is a multi-functional RNA binding protein that regulates histone mRNAs.
Quintas A, Harvey RF, Horvilleur E, Garland GD, Schmidt T, Kalmar L, Dezi V, Marini A, Fulton AM, Pöyry TAA, Cole CH, Turner M, Sawarkar R, Chapman MA, Bushell M, Willis AE. Quintas A, et al. Among authors: poyry taa. Nucleic Acids Res. 2024 Oct 28;52(19):12039-12054. doi: 10.1093/nar/gkae767. Nucleic Acids Res. 2024. PMID: 39225047 Free PMC article.
N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting.
Mulroney TE, Pöyry T, Yam-Puc JC, Rust M, Harvey RF, Kalmar L, Horner E, Booth L, Ferreira AP, Stoneley M, Sawarkar R, Mentzer AJ, Lilley KS, Smales CM, von der Haar T, Turtle L, Dunachie S, Klenerman P, Thaventhiran JED, Willis AE. Mulroney TE, et al. Among authors: poyry t. Nature. 2024 Jan;625(7993):189-194. doi: 10.1038/s41586-023-06800-3. Epub 2023 Dec 6. Nature. 2024. PMID: 38057663 Free PMC article.
Hypoxia: Uncharged tRNA to the Rescue!
Mulroney TE, Pöyry T, Willis AE. Mulroney TE, et al. Among authors: poyry t. Curr Biol. 2021 Jan 11;31(1):R25-R27. doi: 10.1016/j.cub.2020.10.067. Curr Biol. 2021. PMID: 33434482 Free article.
Control of translation elongation in health and disease.
Knight JRP, Garland G, Pöyry T, Mead E, Vlahov N, Sfakianos A, Grosso S, De-Lima-Hedayioglu F, Mallucci GR, von der Haar T, Smales CM, Sansom OJ, Willis AE. Knight JRP, et al. Among authors: poyry t. Dis Model Mech. 2020 Mar 26;13(3):dmm043208. doi: 10.1242/dmm.043208. Dis Model Mech. 2020. PMID: 32298235 Free PMC article. Review.
The cell stress response: extreme times call for post-transcriptional measures.
Pizzinga M, Harvey RF, Garland GD, Mordue R, Dezi V, Ramakrishna M, Sfakianos A, Monti M, Mulroney TE, Poyry T, Willis AE. Pizzinga M, et al. Among authors: poyry t. Wiley Interdiscip Rev RNA. 2020 May;11(3):e1578. doi: 10.1002/wrna.1578. Epub 2019 Nov 21. Wiley Interdiscip Rev RNA. 2020. PMID: 31755249 Review.
Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation.
Soukarieh F, Nowicki MW, Bastide A, Pöyry T, Jones C, Dudek K, Patwardhan G, Meullenet F, Oldham NJ, Walkinshaw MD, Willis AE, Fischer PM. Soukarieh F, et al. Among authors: poyry t. Eur J Med Chem. 2016 Nov 29;124:200-217. doi: 10.1016/j.ejmech.2016.08.047. Epub 2016 Aug 24. Eur J Med Chem. 2016. PMID: 27592390 Free PMC article.
47 results