Frydman J - Search Results

1

State of the science: an update on renal cell carcinoma.

Jonasch E, Futreal PA, Davis IJ, Bailey ST, Kim WY, Brugarolas J, Giaccia AJ, Kurban G, Pause A, Frydman J, Zurita AJ, Rini BI, Sharma P, Atkins MB, Walker CL, Rathmell WK. Jonasch E, et al. Among authors: frydman j. Mol Cancer Res. 2012 Jul;10(7):859-80. doi: 10.1158/1541-7786.MCR-12-0117. Epub 2012 May 25. Mol Cancer Res. 2012. PMID: 22638109 Free PMC article. Review.

2

Modulation of STAT3 folding and function by TRiC/CCT chaperonin.

Kasembeli M, Lau WC, Roh SH, Eckols TK, Frydman J, Chiu W, Tweardy DJ. Kasembeli M, et al. Among authors: frydman j. PLoS Biol. 2014 Apr 22;12(4):e1001844. doi: 10.1371/journal.pbio.1001844. eCollection 2014 Apr. PLoS Biol. 2014. PMID: 24756126 Free PMC article.

3

Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC.

Feldman DE, Thulasiraman V, Ferreyra RG, Frydman J. Feldman DE, et al. Among authors: frydman j. Mol Cell. 1999 Dec;4(6):1051-61. doi: 10.1016/s1097-2765(00)80233-6. Mol Cell. 1999. PMID: 10635329 Free article.

4

Cancers adapt to their mutational load by buffering protein misfolding stress.

Tilk S, Frydman J, Curtis C, Petrov DA. Tilk S, et al. Among authors: frydman j. Elife. 2024 Nov 25;12:RP87301. doi: 10.7554/eLife.87301. Elife. 2024. PMID: 39585785 Free PMC article.

5

The Hsp70 and TRiC/CCT chaperone systems cooperate in vivo to assemble the von Hippel-Lindau tumor suppressor complex.

Melville MW, McClellan AJ, Meyer AS, Darveau A, Frydman J. Melville MW, et al. Among authors: frydman j. Mol Cell Biol. 2003 May;23(9):3141-51. doi: 10.1128/MCB.23.9.3141-3151.2003. Mol Cell Biol. 2003. PMID: 12697815 Free PMC article.

6

Modeling of possible subunit arrangements in the eukaryotic chaperonin TRiC.

Miller EJ, Meyer AS, Frydman J. Miller EJ, et al. Among authors: frydman j. Protein Sci. 2006 Jun;15(6):1522-6. doi: 10.1110/ps.052001606. Epub 2006 May 2. Protein Sci. 2006. PMID: 16672233 Free PMC article.

7

Identification of the TRiC/CCT substrate binding sites uncovers the function of subunit diversity in eukaryotic chaperonins.

Spiess C, Miller EJ, McClellan AJ, Frydman J. Spiess C, et al. Among authors: frydman j. Mol Cell. 2006 Oct 6;24(1):25-37. doi: 10.1016/j.molcel.2006.09.003. Mol Cell. 2006. PMID: 17018290 Free PMC article.

8

Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins.

Reissmann S, Parnot C, Booth CR, Chiu W, Frydman J. Reissmann S, et al. Among authors: frydman j. Nat Struct Mol Biol. 2007 May;14(5):432-40. doi: 10.1038/nsmb1236. Epub 2007 Apr 29. Nat Struct Mol Biol. 2007. PMID: 17460696 Free PMC article.

9

Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT.

Booth CR, Meyer AS, Cong Y, Topf M, Sali A, Ludtke SJ, Chiu W, Frydman J. Booth CR, et al. Among authors: frydman j. Nat Struct Mol Biol. 2008 Jul;15(7):746-53. doi: 10.1038/nsmb.1436. Epub 2008 Jun 8. Nat Struct Mol Biol. 2008. PMID: 18536725 Free PMC article.

10

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies.

Yam AY, Xia Y, Lin HT, Burlingame A, Gerstein M, Frydman J. Yam AY, et al. Among authors: frydman j. Nat Struct Mol Biol. 2008 Dec;15(12):1255-62. doi: 10.1038/nsmb.1515. Epub 2008 Nov 16. Nat Struct Mol Biol. 2008. PMID: 19011634 Free PMC article.

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