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Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris.
Guha S, Baltazar GC, Tu LA, Liu J, Lim JC, Lu W, Argall A, Boesze-Battaglia K, Laties AM, Mitchell CH. Guha S, et al. Among authors: lim jc. J Neurochem. 2012 Aug;122(4):823-33. doi: 10.1111/j.1471-4159.2012.07804.x. Epub 2012 Jun 27. J Neurochem. 2012. PMID: 22639870 Free PMC article.
The P2Y12 Receptor Antagonist Ticagrelor Reduces Lysosomal pH and Autofluorescence in Retinal Pigmented Epithelial Cells From the ABCA4-/- Mouse Model of Retinal Degeneration.
Lu W, Gómez NM, Lim JC, Guha S, O'Brien-Jenkins A, Coffey EE, Campagno KE, McCaughey SA, Laties AM, Carlsson LG, Mitchell CH. Lu W, et al. Among authors: lim jc. Front Pharmacol. 2018 Apr 19;9:242. doi: 10.3389/fphar.2018.00242. eCollection 2018. Front Pharmacol. 2018. PMID: 29725296 Free PMC article.
291 results