Klamerus KJ - Search Results

1

Evaluation of the effect of food on the pharmacokinetics of axitinib in healthy volunteers.

Pithavala YK, Chen Y, Toh M, Selaru P, LaBadie RR, Garrett M, Hee B, Mount J, Ni G, Klamerus KJ, Tortorici MA. Pithavala YK, et al. Among authors: klamerus kj. Cancer Chemother Pharmacol. 2012 Jul;70(1):103-12. doi: 10.1007/s00280-012-1888-9. Epub 2012 May 27. Cancer Chemother Pharmacol. 2012. PMID: 22644797 Clinical Trial.

2

Effect of rifampin on the pharmacokinetics of Axitinib (AG-013736) in Japanese and Caucasian healthy volunteers.

Pithavala YK, Tortorici M, Toh M, Garrett M, Hee B, Kuruganti U, Ni G, Klamerus KJ. Pithavala YK, et al. Among authors: klamerus kj. Cancer Chemother Pharmacol. 2010 Feb;65(3):563-70. doi: 10.1007/s00280-009-1065-y. Epub 2009 Jul 15. Cancer Chemother Pharmacol. 2010. PMID: 19603168 Free PMC article. Clinical Trial.

3

Effect of ketoconazole on the pharmacokinetics of axitinib in healthy volunteers.

Pithavala YK, Tong W, Mount J, Rahavendran SV, Garrett M, Hee B, Selaru P, Sarapa N, Klamerus KJ. Pithavala YK, et al. Among authors: klamerus kj. Invest New Drugs. 2012 Feb;30(1):273-81. doi: 10.1007/s10637-010-9511-6. Epub 2010 Aug 26. Invest New Drugs. 2012. PMID: 20740300 Free PMC article. Clinical Trial.

4

Clinical pharmacology of axitinib.

Chen Y, Tortorici MA, Garrett M, Hee B, Klamerus KJ, Pithavala YK. Chen Y, et al. Among authors: klamerus kj. Clin Pharmacokinet. 2013 Sep;52(9):713-25. doi: 10.1007/s40262-013-0068-3. Clin Pharmacokinet. 2013. PMID: 23677771 Review.

5

Effect of food on the pharmacokinetics of sunitinib malate (SU11248), a multi-targeted receptor tyrosine kinase inhibitor: results from a phase I study in healthy subjects.

Bello CL, Sherman L, Zhou J, Verkh L, Smeraglia J, Mount J, Klamerus KJ. Bello CL, et al. Among authors: klamerus kj. Anticancer Drugs. 2006 Mar;17(3):353-8. doi: 10.1097/00001813-200603000-00015. Anticancer Drugs. 2006. PMID: 16520665 Clinical Trial.

6

Pharmacokinetics, metabolism, and excretion of [14C]axitinib, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in humans.

Smith BJ, Pithavala Y, Bu HZ, Kang P, Hee B, Deese AJ, Pool WF, Klamerus KJ, Wu EY, Dalvie DK. Smith BJ, et al. Among authors: klamerus kj. Drug Metab Dispos. 2014 May;42(5):918-31. doi: 10.1124/dmd.113.056531. Epub 2014 Mar 7. Drug Metab Dispos. 2014. PMID: 24608633 Clinical Trial.

7

Pharmacokinetics of Lorlatinib After Single and Multiple Dosing in Patients with Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer: Results from a Global Phase I/II Study.

Chen J, O'Gorman MT, James LP, Klamerus KJ, Mugundu G, Pithavala YK. Chen J, et al. Among authors: klamerus kj. Clin Pharmacokinet. 2021 Oct;60(10):1313-1324. doi: 10.1007/s40262-021-01015-z. Epub 2021 May 3. Clin Pharmacokinet. 2021. PMID: 33937954 Free PMC article. Clinical Trial.

8

The effect of tafamidis on the QTc interval in healthy subjects.

Klamerus KJ, Watsky E, Moller R, Wang R, Riley S. Klamerus KJ, et al. Br J Clin Pharmacol. 2015 Jun;79(6):918-25. doi: 10.1111/bcp.12561. Br J Clin Pharmacol. 2015. PMID: 25546001 Free PMC article. Clinical Trial.

9

Impact of Acid-Reducing Agents on the Pharmacokinetics of Palbociclib, a Weak Base With pH-Dependent Solubility, With Different Food Intake Conditions.

Sun W, Klamerus KJ, Yuhas LM, Pawlak S, Plotka A, O'Gorman M, Kirkovsky L, Kosa M, Wang D. Sun W, et al. Among authors: klamerus kj. Clin Pharmacol Drug Dev. 2017 Nov;6(6):614-626. doi: 10.1002/cpdd.356. Epub 2017 Apr 21. Clin Pharmacol Drug Dev. 2017. PMID: 28430398 Clinical Trial.

10

Evaluation of the potential interaction between tofacitinib and drugs that undergo renal tubular secretion using metformin, an in vivo marker of renal organic cation transporter 2.

Klamerus KJ, Alvey C, Li L, Feng B, Wang R, Kaplan I, Shi H, Dowty ME, Krishnaswami S. Klamerus KJ, et al. Clin Pharmacol Drug Dev. 2014 Nov;3(6):499-507. doi: 10.1002/cpdd.120. Epub 2014 May 23. Clin Pharmacol Drug Dev. 2014. PMID: 27129125 Clinical Trial.

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