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A validated tumorgraft model reveals activity of dovitinib against renal cell carcinoma.
Sivanand S, Peña-Llopis S, Zhao H, Kucejova B, Spence P, Pavia-Jimenez A, Yamasaki T, McBride DJ, Gillen J, Wolff NC, Morlock L, Lotan Y, Raj GV, Sagalowsky A, Margulis V, Cadeddu JA, Ross MT, Bentley DR, Kabbani W, Xie XJ, Kapur P, Williams NS, Brugarolas J. Sivanand S, et al. Among authors: brugarolas j. Sci Transl Med. 2012 Jun 6;4(137):137ra75. doi: 10.1126/scitranslmed.3003643. Sci Transl Med. 2012. PMID: 22674553 Free PMC article.
Sirolimus in metatastic renal cell carcinoma.
Brugarolas J, Lotan Y, Watumull L, Kabbani W. Brugarolas J, et al. J Clin Oncol. 2008 Jul 10;26(20):3457-60. doi: 10.1200/JCO.2008.16.4590. J Clin Oncol. 2008. PMID: 18612163 No abstract available.
Sirolimus and temsirolimus for epithelioid angiomyolipoma.
Wolff N, Kabbani W, Bradley T, Raj G, Watumull L, Brugarolas J. Wolff N, et al. Among authors: brugarolas j. J Clin Oncol. 2010 Feb 10;28(5):e65-8. doi: 10.1200/JCO.2009.26.3061. Epub 2010 Jan 4. J Clin Oncol. 2010. PMID: 20048172 No abstract available.
Interplay between pVHL and mTORC1 pathways in clear-cell renal cell carcinoma.
Kucejova B, Peña-Llopis S, Yamasaki T, Sivanand S, Tran TA, Alexander S, Wolff NC, Lotan Y, Xie XJ, Kabbani W, Kapur P, Brugarolas J. Kucejova B, et al. Among authors: brugarolas j. Mol Cancer Res. 2011 Sep;9(9):1255-65. doi: 10.1158/1541-7786.MCR-11-0302. Epub 2011 Jul 28. Mol Cancer Res. 2011. PMID: 21798997 Free PMC article.
Regulation of TFEB and V-ATPases by mTORC1.
Peña-Llopis S, Vega-Rubin-de-Celis S, Schwartz JC, Wolff NC, Tran TA, Zou L, Xie XJ, Corey DR, Brugarolas J. Peña-Llopis S, et al. Among authors: brugarolas j. EMBO J. 2011 Jul 29;30(16):3242-58. doi: 10.1038/emboj.2011.257. EMBO J. 2011. PMID: 21804531 Free PMC article.
178 results