Guan KL - Search Results

1

Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors.

Xiao M, Yang H, Xu W, Ma S, Lin H, Zhu H, Liu L, Liu Y, Yang C, Xu Y, Zhao S, Ye D, Xiong Y, Guan KL. Xiao M, et al. Among authors: guan kl. Genes Dev. 2012 Jun 15;26(12):1326-38. doi: 10.1101/gad.191056.112. Epub 2012 Jun 7. Genes Dev. 2012. PMID: 22677546 Free PMC article.

2

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.

Guan KL, Jenkins CW, Li Y, Nichols MA, Wu X, O'Keefe CL, Matera AG, Xiong Y. Guan KL, et al. Genes Dev. 1994 Dec 15;8(24):2939-52. doi: 10.1101/gad.8.24.2939. Genes Dev. 1994. PMID: 8001816 Free article.

3

Identification of functional elements of p18INK4C essential for binding and inhibition of cyclin-dependent kinase (CDK) 4 and CDK6.

Noh SJ, Li Y, Xiong Y, Guan KL. Noh SJ, et al. Among authors: guan kl. Cancer Res. 1999 Feb 1;59(3):558-64. Cancer Res. 1999. PMID: 9973200

4

A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha.

Tang ED, Wang CY, Xiong Y, Guan KL. Tang ED, et al. Among authors: guan kl. J Biol Chem. 2003 Sep 26;278(39):37297-305. doi: 10.1074/jbc.M303389200. Epub 2003 Jul 16. J Biol Chem. 2003. PMID: 12867425 Free article.

5

TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway.

Lei QY, Zhang H, Zhao B, Zha ZY, Bai F, Pei XH, Zhao S, Xiong Y, Guan KL. Lei QY, et al. Among authors: guan kl. Mol Cell Biol. 2008 Apr;28(7):2426-36. doi: 10.1128/MCB.01874-07. Epub 2008 Jan 28. Mol Cell Biol. 2008. PMID: 18227151 Free PMC article.

6

Substrate selectivity APPLies to Akt.

Zhao S, Guan KL. Zhao S, et al. Among authors: guan kl. Cell. 2008 May 2;133(3):399-400. doi: 10.1016/j.cell.2008.04.015. Cell. 2008. PMID: 18455980 Free article.

7

Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.

Yu W, Lin Y, Yao J, Huang W, Lei Q, Xiong Y, Zhao S, Guan KL. Yu W, et al. Among authors: guan kl. J Biol Chem. 2009 May 15;284(20):13669-13675. doi: 10.1074/jbc.M901921200. Epub 2009 Mar 23. J Biol Chem. 2009. PMID: 19318352 Free PMC article.

8

TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.

Zhang H, Liu CY, Zha ZY, Zhao B, Yao J, Zhao S, Xiong Y, Lei QY, Guan KL. Zhang H, et al. Among authors: guan kl. J Biol Chem. 2009 May 15;284(20):13355-13362. doi: 10.1074/jbc.M900843200. Epub 2009 Mar 26. J Biol Chem. 2009. PMID: 19324877 Free PMC article.

9

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha.

Zhao S, Lin Y, Xu W, Jiang W, Zha Z, Wang P, Yu W, Li Z, Gong L, Peng Y, Ding J, Lei Q, Guan KL, Xiong Y. Zhao S, et al. Among authors: guan kl. Science. 2009 Apr 10;324(5924):261-5. doi: 10.1126/science.1170944. Science. 2009. PMID: 19359588 Free PMC article.

10

Structural insights into the YAP and TEAD complex.

Li Z, Zhao B, Wang P, Chen F, Dong Z, Yang H, Guan KL, Xu Y. Li Z, et al. Among authors: guan kl. Genes Dev. 2010 Feb 1;24(3):235-40. doi: 10.1101/gad.1865810. Genes Dev. 2010. PMID: 20123905 Free PMC article.

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