Cameron J - Search Results

1

Serum levels of proprotein convertase subtilisin/kexin type 9 in subjects with familial hypercholesterolemia indicate that proprotein convertase subtilisin/kexin type 9 is cleared from plasma by low-density lipoprotein receptor-independent pathways.

Cameron J, Bogsrud MP, Tveten K, Strøm TB, Holven K, Berge KE, Leren TP. Cameron J, et al. Transl Res. 2012 Aug;160(2):125-30. doi: 10.1016/j.trsl.2012.01.010. Epub 2012 Jan 31. Transl Res. 2012. PMID: 22683370

2

Low-density lipoprotein receptor activity in Epstein-Barr virus-transformed lymphocytes from heterozygotes for the D374Y mutation in the PCSK9 gene.

Holla ØL, Cameron J, Berge KE, Kulseth MA, Ranheim T, Leren TP. Holla ØL, et al. Among authors: cameron j. Scand J Clin Lab Invest. 2006;66(4):317-28. doi: 10.1080/00365510600672775. Scand J Clin Lab Invest. 2006. PMID: 16777760

3

Effect of mutations in the PCSK9 gene on the cell surface LDL receptors.

Cameron J, Holla ØL, Ranheim T, Kulseth MA, Berge KE, Leren TP. Cameron J, et al. Hum Mol Genet. 2006 May 1;15(9):1551-8. doi: 10.1093/hmg/ddl077. Epub 2006 Mar 28. Hum Mol Genet. 2006. PMID: 16571601

4

Degradation of the LDL receptors by PCSK9 is not mediated by a secreted protein acted upon by PCSK9 extracellularly.

Holla ØL, Cameron J, Berge KE, Ranheim T, Leren TP. Holla ØL, et al. Among authors: cameron j. BMC Cell Biol. 2007 Mar 1;8:9. doi: 10.1186/1471-2121-8-9. BMC Cell Biol. 2007. PMID: 17328821 Free PMC article.

5

Berberine decreases PCSK9 expression in HepG2 cells.

Cameron J, Ranheim T, Kulseth MA, Leren TP, Berge KE. Cameron J, et al. Atherosclerosis. 2008 Dec;201(2):266-73. doi: 10.1016/j.atherosclerosis.2008.02.004. Epub 2008 Feb 15. Atherosclerosis. 2008. PMID: 18355829

6

Investigations on the evolutionary conservation of PCSK9 reveal a functionally important protrusion.

Cameron J, Holla ØL, Berge KE, Kulseth MA, Ranheim T, Leren TP, Laerdahl JK. Cameron J, et al. FEBS J. 2008 Aug;275(16):4121-33. doi: 10.1111/j.1742-4658.2008.06553.x. Epub 2008 Jul 9. FEBS J. 2008. PMID: 18631360 Free article.

7

Mutation S462P in the PCSK9 gene reduces secretion of mutant PCSK9 without affecting the autocatalytic cleavage.

Cameron J, Holla ØL, Laerdahl JK, Kulseth MA, Berge KE, Leren TP. Cameron J, et al. Atherosclerosis. 2009 Mar;203(1):161-5. doi: 10.1016/j.atherosclerosis.2008.10.007. Epub 2008 Oct 17. Atherosclerosis. 2009. PMID: 19022446

8

Splice-site mutation c.313+1, G>A in intron 3 of the LDL receptor gene results in transcripts with skipping of exon 3 and inclusion of intron 3.

Cameron J, Holla ØL, Kulseth MA, Leren TP, Berge KE. Cameron J, et al. Clin Chim Acta. 2009 May;403(1-2):131-5. doi: 10.1016/j.cca.2009.02.001. Epub 2009 Feb 7. Clin Chim Acta. 2009. PMID: 19361455

9

A chimeric LDL receptor containing the cytoplasmic domain of the transferrin receptor is degraded by PCSK9.

Holla ØL, Strøm TB, Cameron J, Berge KE, Leren TP. Holla ØL, et al. Among authors: cameron j. Mol Genet Metab. 2010 Feb;99(2):149-56. doi: 10.1016/j.ymgme.2009.09.012. Epub 2009 Sep 27. Mol Genet Metab. 2010. PMID: 19828345

10

Loss-of-function mutation R46L in the PCSK9 gene has little impact on the levels of total serum cholesterol in familial hypercholesterolemia heterozygotes.

Strøm TB, Holla ØL, Cameron J, Berge KE, Leren TP. Strøm TB, et al. Among authors: cameron j. Clin Chim Acta. 2010 Feb;411(3-4):229-33. doi: 10.1016/j.cca.2009.11.008. Epub 2009 Nov 13. Clin Chim Acta. 2010. PMID: 19917273

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