Seefeldt T - Search Results

1

Microtubule S-glutathionylation as a potential approach for antimitotic agents.

Chen W, Seefeldt T, Young A, Zhang X, Zhao Y, Ruffolo J, Kaushik RS, Guan X. Chen W, et al. Among authors: seefeldt t. BMC Cancer. 2012 Jun 15;12:245. doi: 10.1186/1471-2407-12-245. BMC Cancer. 2012. PMID: 22703118 Free PMC article.

2

Design, synthesis, and biological evaluation of N-acetyl-S-(p-chlorophenylcarbamoyl)cysteine and its analogs as a novel class of anticancer agents.

Chen W, Seefeldt T, Young A, Zhang X, Guan X. Chen W, et al. Among authors: seefeldt t. Bioorg Med Chem. 2011 Jan 1;19(1):287-94. doi: 10.1016/j.bmc.2010.11.026. Epub 2010 Nov 13. Bioorg Med Chem. 2011. PMID: 21131205 Free PMC article.

3

Determination of thiols and disulfides via HPLC quantification of 5-thio-2-nitrobenzoic acid.

Chen W, Zhao Y, Seefeldt T, Guan X. Chen W, et al. Among authors: seefeldt t. J Pharm Biomed Anal. 2008 Dec 15;48(5):1375-80. doi: 10.1016/j.jpba.2008.08.033. Epub 2008 Sep 7. J Pharm Biomed Anal. 2008. PMID: 18926658 Free PMC article.

4

Characterization of a novel dithiocarbamate glutathione reductase inhibitor and its use as a tool to modulate intracellular glutathione.

Seefeldt T, Zhao Y, Chen W, Raza AS, Carlson L, Herman J, Stoebner A, Hanson S, Foll R, Guan X. Seefeldt T, et al. J Biol Chem. 2009 Jan 30;284(5):2729-2737. doi: 10.1074/jbc.M802683200. Epub 2008 Dec 2. J Biol Chem. 2009. PMID: 19049979 Free PMC article.

5

Effects of glutathione reductase inhibition on cellular thiol redox state and related systems.

Zhao Y, Seefeldt T, Chen W, Wang X, Matthees D, Hu Y, Guan X. Zhao Y, et al. Among authors: seefeldt t. Arch Biochem Biophys. 2009 May 1;485(1):56-62. doi: 10.1016/j.abb.2009.03.001. Epub 2009 Mar 9. Arch Biochem Biophys. 2009. PMID: 19272349 Free PMC article.

6

Increase in thiol oxidative stress via glutathione reductase inhibition as a novel approach to enhance cancer sensitivity to X-ray irradiation.

Zhao Y, Seefeldt T, Chen W, Carlson L, Stoebner A, Hanson S, Foll R, Matthees DP, Palakurthi S, Guan X. Zhao Y, et al. Among authors: seefeldt t. Free Radic Biol Med. 2009 Jul 15;47(2):176-83. doi: 10.1016/j.freeradbiomed.2009.04.022. Epub 2009 Apr 24. Free Radic Biol Med. 2009. PMID: 19397999 Free PMC article.

7

Evaluation of a dithiocarbamate derivative as an inhibitor of human glutaredoxin-1.

Sadhu SS, Callegari E, Zhao Y, Guan X, Seefeldt T. Sadhu SS, et al. Among authors: seefeldt t. J Enzyme Inhib Med Chem. 2013 Jun;28(3):456-62. doi: 10.3109/14756366.2011.649267. Epub 2012 Feb 3. J Enzyme Inhib Med Chem. 2013. PMID: 22299579 Free PMC article.

8

In-vitro and in-vivo inhibition of melanoma growth and metastasis by the drug combination of celecoxib and dacarbazine.

Sadhu SS, Wang S, Averineni RK, Seefeldt T, Yang Y, Guan X. Sadhu SS, et al. Among authors: seefeldt t. Melanoma Res. 2016 Dec;26(6):572-579. doi: 10.1097/CMR.0000000000000291. Melanoma Res. 2016. PMID: 27540834

9

In Vitro and In Vivo Antimetastatic Effect of Glutathione Disulfide Liposomes.

Sadhu SS, Wang S, Dachineni R, Averineni RK, Seefeldt T, Xie J, Tummala H, Bhat GJ, Guan X. Sadhu SS, et al. Among authors: seefeldt t. Cancer Growth Metastasis. 2017 Mar 8;10:1179064417695255. doi: 10.1177/1179064417695255. eCollection 2017. Cancer Growth Metastasis. 2017. PMID: 28469471 Free PMC article.

10

2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino)- phenylcarbamoylsulfanyl]propionic acid and its derivatives as a novel class of glutathione reductase inhibitors.

Seefeldt T, Dwivedi C, Peitz G, Herman J, Carlson L, Zhang Z, Guan X. Seefeldt T, et al. J Med Chem. 2005 Aug 11;48(16):5224-31. doi: 10.1021/jm050030i. J Med Chem. 2005. PMID: 16078841

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