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Oral administration of the nucleoside EFdA (4'-ethynyl-2-fluoro-2'-deoxyadenosine) provides rapid suppression of HIV viremia in humanized mice and favorable pharmacokinetic properties in mice and the rhesus macaque.
Stoddart CA, Galkina SA, Joshi P, Kosikova G, Moreno ME, Rivera JM, Sloan B, Reeve AB, Sarafianos SG, Murphey-Corb M, Parniak MA. Stoddart CA, et al. Among authors: murphey corb m. Antimicrob Agents Chemother. 2015 Jul;59(7):4190-8. doi: 10.1128/AAC.05036-14. Epub 2015 May 4. Antimicrob Agents Chemother. 2015. PMID: 25941222 Free PMC article.
Longitudinal in vivo positron emission tomography imaging of infected and activated brain macrophages in a macaque model of human immunodeficiency virus encephalitis correlates with central and peripheral markers of encephalitis and areas of synaptic degeneration.
Venneti S, Bonneh-Barkay D, Lopresti BJ, Bissel SJ, Wang G, Mathis CA, Piatak M Jr, Lifson JD, Nyaundi JO, Murphey-Corb M, Wiley CA. Venneti S, et al. Am J Pathol. 2008 Jun;172(6):1603-16. doi: 10.2353/ajpath.2008.070967. Epub 2008 May 8. Am J Pathol. 2008. PMID: 18467697 Free PMC article.
Therapeutic DNA vaccine induces broad T cell responses in the gut and sustained protection from viral rebound and AIDS in SIV-infected rhesus macaques.
Fuller DH, Rajakumar P, Che JW, Narendran A, Nyaundi J, Michael H, Yager EJ, Stagnar C, Wahlberg B, Taber R, Haynes JR, Cook FC, Ertl P, Tite J, Amedee AM, Murphey-Corb M. Fuller DH, et al. Among authors: murphey corb m. PLoS One. 2012;7(3):e33715. doi: 10.1371/journal.pone.0033715. Epub 2012 Mar 19. PLoS One. 2012. PMID: 22442716 Free PMC article.
134 results