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Class II-associated invariant chain peptide down-modulation enhances the immunogenicity of myeloid leukemic blasts resulting in increased CD4+ T-cell responses.
van Luijn MM, Chamuleau ME, Thompson JA, Ostrand-Rosenberg S, Westers TM, Souwer Y, Ossenkoppele GJ, van Ham SM, van de Loosdrecht AA. van Luijn MM, et al. Among authors: van ham sm, van de loosdrecht aa. Haematologica. 2010 Mar;95(3):485-93. doi: 10.3324/haematol.2009.010595. Epub 2009 Nov 10. Haematologica. 2010. PMID: 19903675 Free PMC article.
Alternative Ii-independent antigen-processing pathway in leukemic blasts involves TAP-dependent peptide loading of HLA class II complexes.
van Luijn MM, Chamuleau ME, Ressing ME, Wiertz EJ, Ostrand-Rosenberg S, Souwer Y, Zevenbergen A, Ossenkoppele GJ, van de Loosdrecht AA, van Ham SM. van Luijn MM, et al. Among authors: van ham sm, van de loosdrecht aa. Cancer Immunol Immunother. 2010 Dec;59(12):1825-38. doi: 10.1007/s00262-010-0908-z. Epub 2010 Sep 5. Cancer Immunol Immunother. 2010. PMID: 20820776 Free PMC article.
Targeting Toll-like receptor 7/8 enhances uptake of apoptotic leukemic cells by monocyte-derived dendritic cells but interferes with subsequent cytokine-induced maturation.
van den Ancker W, van Luijn MM, Ruben JM, Westers TM, Bontkes HJ, Ossenkoppele GJ, de Gruijl TD, van de Loosdrecht AA. van den Ancker W, et al. Among authors: van luijn mm, van de loosdrecht aa. Cancer Immunol Immunother. 2011 Jan;60(1):37-47. doi: 10.1007/s00262-010-0917-y. Epub 2010 Sep 22. Cancer Immunol Immunother. 2011. PMID: 20859626 Free PMC article.
Absence of class II-associated invariant chain peptide on leukemic blasts of patients promotes activation of autologous leukemia-reactive CD4+ T cells.
van Luijn MM, van den Ancker W, Chamuleau ME, Zevenbergen A, Westers TM, Ossenkoppele GJ, van Ham SM, van de Loosdrecht AA. van Luijn MM, et al. Among authors: van den ancker w, van ham sm, van de loosdrecht aa. Cancer Res. 2011 Apr 1;71(7):2507-17. doi: 10.1158/0008-5472.CAN-10-3689. Epub 2011 Feb 10. Cancer Res. 2011. PMID: 21310823 Free article.
Promiscuous binding of invariant chain-derived CLIP peptide to distinct HLA-I molecules revealed in leukemic cells.
van Luijn MM, van de Loosdrecht AA, Lampen MH, van Veelen PA, Zevenbergen A, Kester MG, de Ru AH, Ossenkoppele GJ, van Hall T, van Ham SM. van Luijn MM, et al. Among authors: van ham sm, van hall t, van veelen pa, van de loosdrecht aa. PLoS One. 2012;7(4):e34649. doi: 10.1371/journal.pone.0034649. Epub 2012 Apr 26. PLoS One. 2012. PMID: 22563374 Free PMC article.
High class II-associated invariant chain peptide expression on residual leukemic cells is associated with increased relapse risk in acute myeloid leukemia.
van den Ancker W, van Luijn MM, Chamuleau ME, Kelder A, Feller N, Terwijn M, Zevenbergen A, Schuurhuis GJ, van Ham SM, Westers TM, Ossenkoppele GJ, van de Loosdrecht AA. van den Ancker W, et al. Among authors: van ham sm, van luijn mm, van de loosdrecht aa. Leuk Res. 2014 Jun;38(6):691-3. doi: 10.1016/j.leukres.2014.03.014. Epub 2014 Mar 25. Leuk Res. 2014. PMID: 24731748
41 results