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Synthesis and SAR-study for novel arylpiperazine derivatives of 5-arylidenehydantoin with α₁-adrenoceptor antagonistic properties.
Handzlik J, Szymańska E, Wójcik R, Dela A, Jastrzębska-Więsek M, Karolak-Wojciechowska J, Fruziński A, Siwek A, Filipek B, Kieć-Kononowicz K. Handzlik J, et al. Among authors: szymanska e. Bioorg Med Chem. 2012 Jul 15;20(14):4245-57. doi: 10.1016/j.bmc.2012.05.064. Epub 2012 Jun 5. Bioorg Med Chem. 2012. PMID: 22739084
Pharmacophore models based studies on the affinity and selectivity toward 5-HT1A with reference to α1-adrenergic receptors among arylpiperazine derivatives of phenytoin.
Handzlik J, Szymańska E, Nędza K, Kubacka M, Siwek A, Mogilski S, Handzlik J, Filipek B, Kieć-Kononowicz K. Handzlik J, et al. Among authors: szymanska e. Bioorg Med Chem. 2011 Feb 1;19(3):1349-60. doi: 10.1016/j.bmc.2010.11.051. Epub 2010 Dec 5. Bioorg Med Chem. 2011. PMID: 21232965
Amine-alkyl derivatives of hydantoin: new tool to combat resistant bacteria.
Handzlik J, Szymańska E, Chevalier J, Otrębska E, Kieć-Kononowicz K, Pagès JM, Alibert S. Handzlik J, et al. Among authors: szymanska e. Eur J Med Chem. 2011 Dec;46(12):5807-16. doi: 10.1016/j.ejmech.2011.09.032. Epub 2011 Oct 1. Eur J Med Chem. 2011. PMID: 22000919
214 results