Sartorelli AC - Search Results

1

Poly (ADP-ribose) polymerase inhibitors: on the horizon of tailored and personalized therapies for epithelial ovarian cancer.

Ratner ES, Sartorelli AC, Lin ZP. Ratner ES, et al. Among authors: sartorelli ac. Curr Opin Oncol. 2012 Sep;24(5):564-71. doi: 10.1097/CCO.0b013e3283564230. Curr Opin Oncol. 2012. PMID: 22759740 Free PMC article. Review.

2

Triapine disrupts CtIP-mediated homologous recombination repair and sensitizes ovarian cancer cells to PARP and topoisomerase inhibitors.

Lin ZP, Ratner ES, Whicker ME, Lee Y, Sartorelli AC. Lin ZP, et al. Among authors: sartorelli ac. Mol Cancer Res. 2014 Mar;12(3):381-393. doi: 10.1158/1541-7786.MCR-13-0480. Epub 2014 Jan 10. Mol Cancer Res. 2014. PMID: 24413181 Free PMC article.

3

MK-2206 sensitizes BRCA-deficient epithelial ovarian adenocarcinoma to cisplatin and olaparib.

Whicker ME, Lin ZP, Hanna R, Sartorelli AC, Ratner ES. Whicker ME, et al. Among authors: sartorelli ac. BMC Cancer. 2016 Jul 27;16:550. doi: 10.1186/s12885-016-2598-1. BMC Cancer. 2016. PMID: 27465688 Free PMC article.

4

Expression of O⁶-Methylguanine-DNA Methyltransferase Examined by Alkyl-Transfer Assays, Methylation-Specific PCR and Western Blots in Tumors and Matched Normal Tissue.

Ishiguro K, Shyam K, Penketh PG, Baumann RP, Sartorelli AC, Rutherford TJ, Ratner ES. Ishiguro K, et al. Among authors: sartorelli ac. J Cancer Ther. 2013 Jun;4(4):919-931. doi: 10.4236/jct.2013.44103. J Cancer Ther. 2013. PMID: 23946891 Free PMC article.

5

Distinct mechanisms of cell-kill by triapine and its terminally dimethylated derivative Dp44mT due to a loss or gain of activity of their copper(II) complexes.

Ishiguro K, Lin ZP, Penketh PG, Shyam K, Zhu R, Baumann RP, Zhu YL, Sartorelli AC, Rutherford TJ, Ratner ES. Ishiguro K, et al. Among authors: sartorelli ac. Biochem Pharmacol. 2014 Oct 1;91(3):312-22. doi: 10.1016/j.bcp.2014.08.006. Epub 2014 Aug 15. Biochem Pharmacol. 2014. PMID: 25130544 Free PMC article.

6

Triapine potentiates platinum-based combination therapy by disruption of homologous recombination repair.

Ratner ES, Zhu YL, Penketh PG, Berenblum J, Whicker ME, Huang PH, Lee Y, Ishiguro K, Zhu R, Sartorelli AC, Lin ZP. Ratner ES, et al. Among authors: sartorelli ac. Br J Cancer. 2016 Mar 29;114(7):777-86. doi: 10.1038/bjc.2016.54. Epub 2016 Mar 10. Br J Cancer. 2016. PMID: 26964031 Free PMC article.

7

Cataloging antineoplastic agents according to their effectiveness against platinum-resistant and platinum-sensitive ovarian carcinoma cell lines.

Ishiguro K, Zhu YL, Lin ZP, Penketh PG, Shyam K, Zhu R, Baumann RP, Sartorelli AC, Rutherford TJ, Ratner ES. Ishiguro K, et al. Among authors: sartorelli ac. J Transl Sci. 2016;2(2):117-124. doi: 10.15761/JTS.1000127. Epub 2016 Mar 5. J Transl Sci. 2016. PMID: 27076919 Free PMC article.

8

Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors.

Lin ZP, Belcourt MF, Cory JG, Sartorelli AC. Lin ZP, et al. Among authors: sartorelli ac. J Biol Chem. 2004 Jun 25;279(26):27030-8. doi: 10.1074/jbc.M402056200. Epub 2004 Apr 19. J Biol Chem. 2004. PMID: 15096505 Free article.

9

Ataxia-telangiectasia mutated kinase regulates ribonucleotide reductase and mitochondrial homeostasis.

Eaton JS, Lin ZP, Sartorelli AC, Bonawitz ND, Shadel GS. Eaton JS, et al. Among authors: sartorelli ac. J Clin Invest. 2007 Sep;117(9):2723-34. doi: 10.1172/JCI31604. J Clin Invest. 2007. PMID: 17786248 Free PMC article.

10

Reduced level of ribonucleotide reductase R2 subunits increases dependence on homologous recombination repair of cisplatin-induced DNA damage.

Lin ZP, Lee Y, Lin F, Belcourt MF, Li P, Cory JG, Glazer PM, Sartorelli AC. Lin ZP, et al. Among authors: sartorelli ac. Mol Pharmacol. 2011 Dec;80(6):1000-12. doi: 10.1124/mol.111.074708. Epub 2011 Aug 29. Mol Pharmacol. 2011. PMID: 21875941 Free PMC article.

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