Lu Y - Search Results

1

Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS.

González-Pérez P, Lu Y, Chian RJ, Sapp PC, Tanzi RE, Bertram L, McKenna-Yasek D, Gao FB, Brown RH Jr. González-Pérez P, et al. Among authors: lu y. Neurobiol Dis. 2012 Dec;48(3):391-8. doi: 10.1016/j.nbd.2012.06.018. Epub 2012 Jul 3. Neurobiol Dis. 2012. PMID: 22766032 Free PMC article.

2

The FTD/ALS-associated RNA-binding protein TDP-43 regulates the robustness of neuronal specification through microRNA-9a in Drosophila.

Li Z, Lu Y, Xu XL, Gao FB. Li Z, et al. Among authors: lu y. Hum Mol Genet. 2013 Jan 15;22(2):218-25. doi: 10.1093/hmg/dds420. Epub 2012 Oct 5. Hum Mol Genet. 2013. PMID: 23042786 Free PMC article.

3

Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching.

Lu Y, Ferris J, Gao FB. Lu Y, et al. Mol Brain. 2009 Sep 25;2:30. doi: 10.1186/1756-6606-2-30. Mol Brain. 2009. PMID: 19781077 Free PMC article.

4

Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations.

Zhang Z, Almeida S, Lu Y, Nishimura AL, Peng L, Sun D, Wu B, Karydas AM, Tartaglia MC, Fong JC, Miller BL, Farese RV Jr, Moore MJ, Shaw CE, Gao FB. Zhang Z, et al. Among authors: lu y. PLoS One. 2013 Oct 15;8(10):e76055. doi: 10.1371/journal.pone.0076055. eCollection 2013. PLoS One. 2013. PMID: 24143176 Free PMC article.

5

FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions.

Yang D, Abdallah A, Li Z, Lu Y, Almeida S, Gao FB. Yang D, et al. Among authors: lu y. Acta Neuropathol. 2015 Oct;130(4):525-35. doi: 10.1007/s00401-015-1448-6. Epub 2015 Jun 2. Acta Neuropathol. 2015. PMID: 26031661 Free PMC article.

6

TBK1 haploinsufficiency in ALS and FTD compromises membrane trafficking.

Lu Y, Almeida S, Gao FB. Lu Y, et al. Acta Neuropathol. 2021 Jul;142(1):217-221. doi: 10.1007/s00401-021-02331-1. Epub 2021 Jun 3. Acta Neuropathol. 2021. PMID: 34081168 Free PMC article. No abstract available.

7

Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons.

Lopez-Gonzalez R, Lu Y, Gendron TF, Karydas A, Tran H, Yang D, Petrucelli L, Miller BL, Almeida S, Gao FB. Lopez-Gonzalez R, et al. Among authors: lu y. Neuron. 2016 Oct 19;92(2):383-391. doi: 10.1016/j.neuron.2016.09.015. Epub 2016 Oct 6. Neuron. 2016. PMID: 27720481 Free PMC article.

8

Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia.

West RJ, Lu Y, Marie B, Gao FB, Sweeney ST. West RJ, et al. Among authors: lu y. J Cell Biol. 2015 Mar 30;208(7):931-47. doi: 10.1083/jcb.201404066. Epub 2015 Mar 23. J Cell Biol. 2015. PMID: 25800055 Free PMC article.

9

Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS.

Tran H, Almeida S, Moore J, Gendron TF, Chalasani U, Lu Y, Du X, Nickerson JA, Petrucelli L, Weng Z, Gao FB. Tran H, et al. Among authors: lu y. Neuron. 2015 Sep 23;87(6):1207-1214. doi: 10.1016/j.neuron.2015.09.015. Neuron. 2015. PMID: 26402604 Free PMC article.

10

Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal dementia, is required for autophagosome maturation.

Lu Y, Zhang Z, Sun D, Sweeney ST, Gao FB. Lu Y, et al. Mol Cell. 2013 Oct 24;52(2):264-71. doi: 10.1016/j.molcel.2013.08.041. Epub 2013 Oct 3. Mol Cell. 2013. PMID: 24095276 Free PMC article.

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