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Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood.
Jung SM, Moroi M, Soejima K, Nakagaki T, Miura Y, Berndt MC, Gardiner EE, Howes JM, Pugh N, Bihan D, Watson SP, Farndale RW. Jung SM, et al. Among authors: howes jm. J Biol Chem. 2012 Aug 24;287(35):30000-13. doi: 10.1074/jbc.M112.359125. Epub 2012 Jul 6. J Biol Chem. 2012. PMID: 22773837 Free PMC article. Clinical Trial.
Proteomic profiling of platelet signalling.
Howes JM. Howes JM. Expert Rev Proteomics. 2013 Aug;10(4):355-64. doi: 10.1586/14789450.2013.820534. Expert Rev Proteomics. 2013. PMID: 23992418 Review.
Complement C3 is a novel plasma clot component with anti-fibrinolytic properties.
Howes JM, Richardson VR, Smith KA, Schroeder V, Somani R, Shore A, Hess K, Ajjan R, Pease RJ, Keen JN, Standeven KF, Carter AM. Howes JM, et al. Diab Vasc Dis Res. 2012 Jul;9(3):216-25. doi: 10.1177/1479164111432788. Epub 2012 Jan 17. Diab Vasc Dis Res. 2012. PMID: 22253322 Free article.
24 results