Botchan MR - Search Results

1

ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryote.

Lyubimov AY, Costa A, Bleichert F, Botchan MR, Berger JM. Lyubimov AY, et al. Among authors: botchan mr. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):11999-2004. doi: 10.1073/pnas.1209406109. Epub 2012 Jul 9. Proc Natl Acad Sci U S A. 2012. PMID: 22778422 Free PMC article.

2

The structural basis for MCM2-7 helicase activation by GINS and Cdc45.

Costa A, Ilves I, Tamberg N, Petojevic T, Nogales E, Botchan MR, Berger JM. Costa A, et al. Among authors: botchan mr. Nat Struct Mol Biol. 2011 Apr;18(4):471-7. doi: 10.1038/nsmb.2004. Epub 2011 Mar 6. Nat Struct Mol Biol. 2011. PMID: 21378962 Free PMC article.

3

Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement.

Petojevic T, Pesavento JJ, Costa A, Liang J, Wang Z, Berger JM, Botchan MR. Petojevic T, et al. Among authors: botchan mr. Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):E249-58. doi: 10.1073/pnas.1422003112. Epub 2015 Jan 5. Proc Natl Acad Sci U S A. 2015. PMID: 25561522 Free PMC article.

4

Conformational control and DNA-binding mechanism of the metazoan origin recognition complex.

Bleichert F, Leitner A, Aebersold R, Botchan MR, Berger JM. Bleichert F, et al. Among authors: botchan mr. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E5906-E5915. doi: 10.1073/pnas.1806315115. Epub 2018 Jun 13. Proc Natl Acad Sci U S A. 2018. PMID: 29899147 Free PMC article.

5

Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.

Eickhoff P, Kose HB, Martino F, Petojevic T, Abid Ali F, Locke J, Tamberg N, Nans A, Berger JM, Botchan MR, Yardimci H, Costa A. Eickhoff P, et al. Among authors: botchan mr. Cell Rep. 2019 Sep 3;28(10):2673-2688.e8. doi: 10.1016/j.celrep.2019.07.104. Cell Rep. 2019. PMID: 31484077 Free PMC article.

6

Nucleotide-dependent conformational changes in the DnaA-like core of the origin recognition complex.

Clarey MG, Erzberger JP, Grob P, Leschziner AE, Berger JM, Nogales E, Botchan M. Clarey MG, et al. Nat Struct Mol Biol. 2006 Aug;13(8):684-90. doi: 10.1038/nsmb1121. Epub 2006 Jul 9. Nat Struct Mol Biol. 2006. PMID: 16829958

7

DNA replication: making two forks from one prereplication complex.

Botchan M, Berger J. Botchan M, et al. Mol Cell. 2010 Dec 22;40(6):860-1. doi: 10.1016/j.molcel.2010.12.014. Mol Cell. 2010. PMID: 21172652 Free PMC article.

8

A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation.

Bleichert F, Balasov M, Chesnokov I, Nogales E, Botchan MR, Berger JM. Bleichert F, et al. Among authors: botchan mr. Elife. 2013 Oct 8;2:e00882. doi: 10.7554/eLife.00882. Elife. 2013. PMID: 24137536 Free PMC article.

9

DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome.

Costa A, Renault L, Swuec P, Petojevic T, Pesavento JJ, Ilves I, MacLellan-Gibson K, Fleck RA, Botchan MR, Berger JM. Costa A, et al. Among authors: botchan mr. Elife. 2014 Aug 12;3:e03273. doi: 10.7554/eLife.03273. Elife. 2014. PMID: 25117490 Free PMC article.

10

Crystal structure of the eukaryotic origin recognition complex.

Bleichert F, Botchan MR, Berger JM. Bleichert F, et al. Among authors: botchan mr. Nature. 2015 Mar 19;519(7543):321-6. doi: 10.1038/nature14239. Epub 2015 Mar 11. Nature. 2015. PMID: 25762138 Free PMC article.

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