Costa A - Search Results

1

ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryote.

Lyubimov AY, Costa A, Bleichert F, Botchan MR, Berger JM. Lyubimov AY, et al. Among authors: costa a. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):11999-2004. doi: 10.1073/pnas.1209406109. Epub 2012 Jul 9. Proc Natl Acad Sci U S A. 2012. PMID: 22778422 Free PMC article.

2

Intersubunit allosteric communication mediated by a conserved loop in the MCM helicase.

Barry ER, Lovett JE, Costa A, Lea SM, Bell SD. Barry ER, et al. Among authors: costa a. Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1051-6. doi: 10.1073/pnas.0809192106. Epub 2009 Jan 21. Proc Natl Acad Sci U S A. 2009. PMID: 19164574 Free PMC article.

3

Molecular determinants of origin discrimination by Orc1 initiators in archaea.

Dueber EC, Costa A, Corn JE, Bell SD, Berger JM. Dueber EC, et al. Among authors: costa a. Nucleic Acids Res. 2011 May;39(9):3621-31. doi: 10.1093/nar/gkq1308. Epub 2011 Jan 11. Nucleic Acids Res. 2011. PMID: 21227921 Free PMC article.

4

The structural basis for MCM2-7 helicase activation by GINS and Cdc45.

Costa A, Ilves I, Tamberg N, Petojevic T, Nogales E, Botchan MR, Berger JM. Costa A, et al. Nat Struct Mol Biol. 2011 Apr;18(4):471-7. doi: 10.1038/nsmb.2004. Epub 2011 Mar 6. Nat Struct Mol Biol. 2011. PMID: 21378962 Free PMC article.

5

Mechanisms for initiating cellular DNA replication.

Costa A, Hood IV, Berger JM. Costa A, et al. Annu Rev Biochem. 2013;82:25-54. doi: 10.1146/annurev-biochem-052610-094414. Annu Rev Biochem. 2013. PMID: 23746253 Free PMC article. Review.

6

DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome.

Costa A, Renault L, Swuec P, Petojevic T, Pesavento JJ, Ilves I, MacLellan-Gibson K, Fleck RA, Botchan MR, Berger JM. Costa A, et al. Elife. 2014 Aug 12;3:e03273. doi: 10.7554/eLife.03273. Elife. 2014. PMID: 25117490 Free PMC article.

7

Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement.

Petojevic T, Pesavento JJ, Costa A, Liang J, Wang Z, Berger JM, Botchan MR. Petojevic T, et al. Among authors: costa a. Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):E249-58. doi: 10.1073/pnas.1422003112. Epub 2015 Jan 5. Proc Natl Acad Sci U S A. 2015. PMID: 25561522 Free PMC article.

8

Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: insights from DNA complex structures.

Pike AC, Gomathinayagam S, Swuec P, Berti M, Zhang Y, Schnecke C, Marino F, von Delft F, Renault L, Costa A, Gileadi O, Vindigni A. Pike AC, et al. Among authors: costa a. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4286-91. doi: 10.1073/pnas.1417594112. Epub 2015 Mar 23. Proc Natl Acad Sci U S A. 2015. PMID: 25831490 Free PMC article.

9

CMG-Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome.

Zhou JC, Janska A, Goswami P, Renault L, Abid Ali F, Kotecha A, Diffley JFX, Costa A. Zhou JC, et al. Among authors: costa a. Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4141-4146. doi: 10.1073/pnas.1700530114. Epub 2017 Apr 3. Proc Natl Acad Sci U S A. 2017. PMID: 28373564 Free PMC article.

10

Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.

Eickhoff P, Kose HB, Martino F, Petojevic T, Abid Ali F, Locke J, Tamberg N, Nans A, Berger JM, Botchan MR, Yardimci H, Costa A. Eickhoff P, et al. Among authors: costa a. Cell Rep. 2019 Sep 3;28(10):2673-2688.e8. doi: 10.1016/j.celrep.2019.07.104. Cell Rep. 2019. PMID: 31484077 Free PMC article.

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