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Page 1
T regulatory cell separation for clinical application.
Di Ianni M, Del Papa B, Zei T, Iacucci Ostini R, Cecchini D, Cantelmi MG, Baldoni S, Sportoletti P, Cavalli L, Carotti A, Pierini A, Falini B, Martelli MF, Falzetti F. Di Ianni M, et al. Among authors: iacucci ostini r. Transfus Apher Sci. 2012 Oct;47(2):213-6. doi: 10.1016/j.transci.2012.06.007. Epub 2012 Jul 12. Transfus Apher Sci. 2012. PMID: 22795999 Review.
Graft engineering for allogeneic haploidentical stem cell transplantation.
Tabilio A, Falzetti F, Zei T, De Ioanni M, Bonifacio E, Battelli F, Iacucci Ostini R, Ballanti S, Cimminiello M, Capponi M, Silvani C, Minelli O, Fettucciari K, Marconi P, Rosati E, Santucci A, Di Ianni M, Aversa F, Martelli MF. Tabilio A, et al. Among authors: iacucci ostini r. Blood Cells Mol Dis. 2004 Nov-Dec;33(3):274-80. doi: 10.1016/j.bcmd.2004.08.016. Blood Cells Mol Dis. 2004. PMID: 15528144 Review.
HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse.
Martelli MF, Di Ianni M, Ruggeri L, Falzetti F, Carotti A, Terenzi A, Pierini A, Massei MS, Amico L, Urbani E, Del Papa B, Zei T, Iacucci Ostini R, Cecchini D, Tognellini R, Reisner Y, Aversa F, Falini B, Velardi A. Martelli MF, et al. Among authors: iacucci ostini r. Blood. 2014 Jul 24;124(4):638-44. doi: 10.1182/blood-2014-03-564401. Epub 2014 Jun 12. Blood. 2014. PMID: 24923299 Free article. Clinical Trial.
The NOTCH1/CD39 axis: a Treg trip-switch for GvHD.
Del Papa B, Pierini A, Sportoletti P, Baldoni S, Cecchini D, Rosati E, Dorillo E, Aureli P, Zei T, Iacucci Ostini R, Ruggeri L, Carotti A, Velardi A, Negrin R, Martelli MF, Falzetti F, Di Ianni M. Del Papa B, et al. Among authors: iacucci ostini r. Leukemia. 2016 Sep;30(9):1931-4. doi: 10.1038/leu.2016.87. Epub 2016 Apr 29. Leukemia. 2016. PMID: 27125307 No abstract available.
Clinical-Grade-Expanded Regulatory T Cells Prevent Graft-versus-Host Disease While Allowing a Powerful T Cell-Dependent Graft-versus-Leukemia Effect in Murine Models.
Del Papa B, Ruggeri L, Urbani E, Baldoni S, Cecchini D, Zei T, Iacucci Ostini R, Crescenzi B, Carotti A, Pierini A, Sportoletti P, Di Bartolomeo P, Falzetti F, Mecucci C, Velardi A, Martelli MF, Di Ianni M. Del Papa B, et al. Among authors: iacucci ostini r. Biol Blood Marrow Transplant. 2017 Nov;23(11):1847-1851. doi: 10.1016/j.bbmt.2017.07.009. Epub 2017 Jul 17. Biol Blood Marrow Transplant. 2017. PMID: 28729148 Free article.
Decreased NOTCH1 Activation Correlates with Response to Ibrutinib in Chronic Lymphocytic Leukemia.
Del Papa B, Baldoni S, Dorillo E, De Falco F, Rompietti C, Cecchini D, Cantelmi MG, Sorcini D, Nogarotto M, Adamo FM, Mezzasoma F, Silva Barcelos EC, Albi E, Iacucci Ostini R, Di Tommaso A, Marra A, Montanaro G, Martelli MP, Falzetti F, Di Ianni M, Rosati E, Sportoletti P. Del Papa B, et al. Among authors: iacucci ostini r. Clin Cancer Res. 2019 Dec 15;25(24):7540-7553. doi: 10.1158/1078-0432.CCR-19-1009. Epub 2019 Oct 2. Clin Cancer Res. 2019. PMID: 31578228
Haploidentical age-adapted myeloablative transplant and regulatory and effector T cells for acute myeloid leukemia.
Pierini A, Ruggeri L, Carotti A, Falzetti F, Saldi S, Terenzi A, Zucchetti C, Ingrosso G, Zei T, Iacucci Ostini R, Piccinelli S, Bonato S, Tricarico S, Mancusi A, Ciardelli S, Limongello R, Merluzzi M, Di Ianni M, Tognellini R, Minelli O, Mecucci C, Martelli MP, Falini B, Martelli MF, Aristei C, Velardi A. Pierini A, et al. Among authors: iacucci ostini r. Blood Adv. 2021 Mar 9;5(5):1199-1208. doi: 10.1182/bloodadvances.2020003739. Blood Adv. 2021. PMID: 33646302 Free PMC article.
HLA-haploidentical hematopoietic stem cells transplantation with regulatory and conventional T-cell adoptive immunotherapy in pediatric patients with very high-risk acute leukemia.
Massei MS, Capolsini I, Mastrodicasa E, Perruccio K, Arcioni F, Cerri C, Gurdo G, Sciabolacci S, Falzetti F, Zei T, Iacucci Ostini R, Brogna M, Panizza BM, Saldi S, Merluzzi M, Tognellini R, Marchesi M, Minelli O, Aristei C, Velardi A, Pierini A, Ruggeri L, Martelli MF, Carotti A, Caniglia M. Massei MS, et al. Among authors: iacucci ostini r. Bone Marrow Transplant. 2023 May;58(5):526-533. doi: 10.1038/s41409-023-01911-x. Epub 2023 Feb 11. Bone Marrow Transplant. 2023. PMID: 36774432 Free PMC article.
Blinatumomab Redirects Donor Lymphocytes against CD19+ Acute Lymphoblastic Leukemia without Relevant Bystander Alloreactivity after Haploidentical Hematopoietic Stem Cell Transplantation.
Mancusi A, Zorutti F, Ruggeri L, Bonato S, Tricarico S, Zei T, Iacucci Ostini R, Viglione V, Sembenico R, Sciabolacci S, Cardinali V, Martelli MF, Mecucci C, Carotti A, Martelli MP, Velardi A, Pierini A. Mancusi A, et al. Among authors: iacucci ostini r. Int J Mol Sci. 2023 Nov 9;24(22):16105. doi: 10.3390/ijms242216105. Int J Mol Sci. 2023. PMID: 38003295 Free PMC article.
The Leukemic Isocitrate Dehydrogenase (IDH) 1/2 Mutations Impair Myeloid and Erythroid Cell Differentiation of Primary Human Hematopoietic Stem and Progenitor Cells (HSPCs).
Pierangeli S, Donnini S, Ciaurro V, Milano F, Cardinali V, Sciabolacci S, Cimino G, Gionfriddo I, Ranieri R, Cipriani S, Padiglioni E, Iacucci Ostini R, Zei T, Pierini A, Martelli MP. Pierangeli S, et al. Among authors: iacucci ostini r. Cancers (Basel). 2024 Jul 27;16(15):2675. doi: 10.3390/cancers16152675. Cancers (Basel). 2024. PMID: 39123404 Free PMC article.