Pratt EB - Search Results

1

Engineered interaction between SUR1 and Kir6.2 that enhances ATP sensitivity in KATP channels.

Pratt EB, Zhou Q, Gay JW, Shyng SL. Pratt EB, et al. J Gen Physiol. 2012 Aug;140(2):175-87. doi: 10.1085/jgp.201210803. Epub 2012 Jul 16. J Gen Physiol. 2012. PMID: 22802363 Free PMC article.

2

Kir6.2 mutations associated with neonatal diabetes reduce expression of ATP-sensitive K+ channels: implications in disease mechanism and sulfonylurea therapy.

Lin CW, Lin YW, Yan FF, Casey J, Kochhar M, Pratt EB, Shyng SL. Lin CW, et al. Among authors: pratt eb. Diabetes. 2006 Jun;55(6):1738-46. doi: 10.2337/db05-1571. Diabetes. 2006. PMID: 16731837

3

Sulfonylurea receptor 1 mutations that cause opposite insulin secretion defects with chemical chaperone exposure.

Pratt EB, Yan FF, Gay JW, Stanley CA, Shyng SL. Pratt EB, et al. J Biol Chem. 2009 Mar 20;284(12):7951-9. doi: 10.1074/jbc.M807012200. Epub 2009 Jan 16. J Biol Chem. 2009. PMID: 19151370 Free PMC article.

4

Role of Hsp90 in biogenesis of the beta-cell ATP-sensitive potassium channel complex.

Yan FF, Pratt EB, Chen PC, Wang F, Skach WR, David LL, Shyng SL. Yan FF, et al. Among authors: pratt eb. Mol Biol Cell. 2010 Jun 15;21(12):1945-54. doi: 10.1091/mbc.e10-02-0116. Epub 2010 Apr 28. Mol Biol Cell. 2010. PMID: 20427569 Free PMC article.

5

N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2.

Pratt EB, Tewson P, Bruederle CE, Skach WR, Shyng SL. Pratt EB, et al. J Gen Physiol. 2011 Mar;137(3):299-314. doi: 10.1085/jgp.201010557. Epub 2011 Feb 14. J Gen Physiol. 2011. PMID: 21321069 Free PMC article.

6

ATP activates ATP-sensitive potassium channels composed of mutant sulfonylurea receptor 1 and Kir6.2 with diminished PIP2 sensitivity.

Pratt EB, Shyng SL. Pratt EB, et al. Channels (Austin). 2011 Jul-Aug;5(4):314-9. doi: 10.4161/chan.5.4.16510. Epub 2011 Jul 1. Channels (Austin). 2011. PMID: 21654216 Free PMC article.

7

Engineered Kir6.2 mutations that correct the trafficking defect of K(ATP) channels caused by specific SUR1 mutations.

Zhou Q, Pratt EB, Shyng SL. Zhou Q, et al. Among authors: pratt eb. Channels (Austin). 2013 Jul-Aug;7(4):313-7. doi: 10.4161/chan.25003. Epub 2013 May 21. Channels (Austin). 2013. PMID: 23695995 Free PMC article.

8

Down-regulation of ZnT8 expression in INS-1 rat pancreatic beta cells reduces insulin content and glucose-inducible insulin secretion.

Fu Y, Tian W, Pratt EB, Dirling LB, Shyng SL, Meshul CK, Cohen DM. Fu Y, et al. Among authors: pratt eb. PLoS One. 2009 May 25;4(5):e5679. doi: 10.1371/journal.pone.0005679. PLoS One. 2009. PMID: 19479076 Free PMC article.

9

Use-dependent inhibition of P2X3 receptors by nanomolar agonist.

Pratt EB, Brink TS, Bergson P, Voigt MM, Cook SP. Pratt EB, et al. J Neurosci. 2005 Aug 10;25(32):7359-65. doi: 10.1523/JNEUROSCI.5189-04.2005. J Neurosci. 2005. PMID: 16093386 Free PMC article.

10

The cell giveth and the cell taketh away: an overview of Notch pathway activation by endocytic trafficking of ligands and receptors.

Pratt EB, Wentzell JS, Maxson JE, Courter L, Hazelett D, Christian JL. Pratt EB, et al. Acta Histochem. 2011 May;113(3):248-55. doi: 10.1016/j.acthis.2010.01.006. Epub 2010 Feb 1. Acta Histochem. 2011. PMID: 20122714 Free PMC article. Review.

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