Shyng SL - Search Results

1

Engineered interaction between SUR1 and Kir6.2 that enhances ATP sensitivity in KATP channels.

Pratt EB, Zhou Q, Gay JW, Shyng SL. Pratt EB, et al. Among authors: shyng sl. J Gen Physiol. 2012 Aug;140(2):175-87. doi: 10.1085/jgp.201210803. Epub 2012 Jul 16. J Gen Physiol. 2012. PMID: 22802363 Free PMC article.

2

Defective trafficking and function of KATP channels caused by a sulfonylurea receptor 1 mutation associated with persistent hyperinsulinemic hypoglycemia of infancy.

Cartier EA, Conti LR, Vandenberg CA, Shyng SL. Cartier EA, et al. Among authors: shyng sl. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2882-7. doi: 10.1073/pnas.051499698. Proc Natl Acad Sci U S A. 2001. PMID: 11226335 Free PMC article.

3

Identification of a familial hyperinsulinism-causing mutation in the sulfonylurea receptor 1 that prevents normal trafficking and function of KATP channels.

Taschenberger G, Mougey A, Shen S, Lester LB, LaFranchi S, Shyng SL. Taschenberger G, et al. Among authors: shyng sl. J Biol Chem. 2002 May 10;277(19):17139-46. doi: 10.1074/jbc.M200363200. Epub 2002 Feb 26. J Biol Chem. 2002. PMID: 11867634 Free article.

4

Modulation of the trafficking efficiency and functional properties of ATP-sensitive potassium channels through a single amino acid in the sulfonylurea receptor.

Cartier EA, Shen S, Shyng SL. Cartier EA, et al. Among authors: shyng sl. J Biol Chem. 2003 Feb 28;278(9):7081-90. doi: 10.1074/jbc.M211395200. Epub 2002 Dec 21. J Biol Chem. 2003. PMID: 12496311 Free article.

5

Stabilization of the activity of ATP-sensitive potassium channels by ion pairs formed between adjacent Kir6.2 subunits.

Lin YW, Jia T, Weinsoft AM, Shyng SL. Lin YW, et al. Among authors: shyng sl. J Gen Physiol. 2003 Aug;122(2):225-37. doi: 10.1085/jgp.200308822. J Gen Physiol. 2003. PMID: 12885877 Free PMC article.

6

Sulfonylureas correct trafficking defects of ATP-sensitive potassium channels caused by mutations in the sulfonylurea receptor.

Yan F, Lin CW, Weisiger E, Cartier EA, Taschenberger G, Shyng SL. Yan F, et al. Among authors: shyng sl. J Biol Chem. 2004 Mar 19;279(12):11096-105. doi: 10.1074/jbc.M312810200. Epub 2004 Jan 5. J Biol Chem. 2004. PMID: 14707124 Free article.

7

Role of ubiquitin-proteasome degradation pathway in biogenesis efficiency of {beta}-cell ATP-sensitive potassium channels.

Yan FF, Lin CW, Cartier EA, Shyng SL. Yan FF, et al. Among authors: shyng sl. Am J Physiol Cell Physiol. 2005 Nov;289(5):C1351-9. doi: 10.1152/ajpcell.00240.2005. Epub 2005 Jun 29. Am J Physiol Cell Physiol. 2005. PMID: 15987767 Free PMC article.

8

A novel KCNJ11 mutation associated with congenital hyperinsulinism reduces the intrinsic open probability of beta-cell ATP-sensitive potassium channels.

Lin YW, MacMullen C, Ganguly A, Stanley CA, Shyng SL. Lin YW, et al. Among authors: shyng sl. J Biol Chem. 2006 Feb 3;281(5):3006-12. doi: 10.1074/jbc.M511875200. Epub 2005 Dec 6. J Biol Chem. 2006. PMID: 16332676 Free PMC article.

9

Kir6.2 mutations associated with neonatal diabetes reduce expression of ATP-sensitive K+ channels: implications in disease mechanism and sulfonylurea therapy.

Lin CW, Lin YW, Yan FF, Casey J, Kochhar M, Pratt EB, Shyng SL. Lin CW, et al. Among authors: shyng sl. Diabetes. 2006 Jun;55(6):1738-46. doi: 10.2337/db05-1571. Diabetes. 2006. PMID: 16731837

10

Sulfonylureas correct trafficking defects of disease-causing ATP-sensitive potassium channels by binding to the channel complex.

Yan FF, Casey J, Shyng SL. Yan FF, et al. Among authors: shyng sl. J Biol Chem. 2006 Nov 3;281(44):33403-13. doi: 10.1074/jbc.M605195200. Epub 2006 Sep 6. J Biol Chem. 2006. PMID: 16956886 Free article.

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