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Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases.
Vandenbroucke RE, Dejonckheere E, Van Lint P, Demeestere D, Van Wonterghem E, Vanlaere I, Puimège L, Van Hauwermeiren F, De Rycke R, Mc Guire C, Campestre C, López-Otin C, Matthys P, Leclercq G, Libert C. Vandenbroucke RE, et al. Among authors: van wonterghem e, van hauwermeiren f, van lint p. J Neurosci. 2012 Jul 18;32(29):9805-16. doi: 10.1523/JNEUROSCI.0967-12.2012. J Neurosci. 2012. PMID: 22815495 Free PMC article.
Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF.
Vandenbroucke RE, Dejonckheere E, Van Hauwermeiren F, Lodens S, De Rycke R, Van Wonterghem E, Staes A, Gevaert K, López-Otin C, Libert C. Vandenbroucke RE, et al. Among authors: van wonterghem e, van hauwermeiren f. EMBO Mol Med. 2013 Jul;5(7):1000-16. doi: 10.1002/emmm.201202100. Epub 2013 May 30. EMBO Mol Med. 2013. PMID: 23723167 Free PMC article.
Pro-inflammatory effects of matrix metalloproteinase 7 in acute inflammation.
Vandenbroucke RE, Vanlaere I, Van Hauwermeiren F, Van Wonterghem E, Wilson C, Libert C. Vandenbroucke RE, et al. Among authors: van wonterghem e, van hauwermeiren f. Mucosal Immunol. 2014 May;7(3):579-88. doi: 10.1038/mi.2013.76. Epub 2013 Oct 16. Mucosal Immunol. 2014. PMID: 24129163 Free article.
TNFR1-induced lethal inflammation is mediated by goblet and Paneth cell dysfunction.
Van Hauwermeiren F, Vandenbroucke RE, Grine L, Lodens S, Van Wonterghem E, De Rycke R, De Geest N, Hassan B, Libert C. Van Hauwermeiren F, et al. Among authors: van wonterghem e. Mucosal Immunol. 2015 Jul;8(4):828-40. doi: 10.1038/mi.2014.112. Epub 2014 Nov 26. Mucosal Immunol. 2015. PMID: 25425265 Free article.
Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation.
Dejager L, Dendoncker K, Eggermont M, Souffriau J, Van Hauwermeiren F, Willart M, Van Wonterghem E, Naessens T, Ballegeer M, Vandevyver S, Hammad H, Lambrecht B, De Bosscher K, Grooten J, Libert C. Dejager L, et al. Among authors: van wonterghem e, van hauwermeiren f. Mucosal Immunol. 2015 Nov;8(6):1212-25. doi: 10.1038/mi.2015.12. Epub 2015 Mar 11. Mucosal Immunol. 2015. PMID: 25760421 Free article.
Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.
Vanden Berghe T, Hulpiau P, Martens L, Vandenbroucke RE, Van Wonterghem E, Perry SW, Bruggeman I, Divert T, Choi SM, Vuylsteke M, Shestopalov VI, Libert C, Vandenabeele P. Vanden Berghe T, et al. Among authors: van wonterghem e. Immunity. 2015 Jul 21;43(1):200-9. doi: 10.1016/j.immuni.2015.06.011. Epub 2015 Jul 7. Immunity. 2015. PMID: 26163370 Free PMC article.
47 results