Jochemsen A - Search Results

1

MDM4 is a key therapeutic target in cutaneous melanoma.

Gembarska A, Luciani F, Fedele C, Russell EA, Dewaele M, Villar S, Zwolinska A, Haupt S, de Lange J, Yip D, Goydos J, Haigh JJ, Haupt Y, Larue L, Jochemsen A, Shi H, Moriceau G, Lo RS, Ghanem G, Shackleton M, Bernal F, Marine JC. Gembarska A, et al. Among authors: jochemsen a. Nat Med. 2012 Aug;18(8):1239-47. doi: 10.1038/nm.2863. Epub 2012 Jul 22. Nat Med. 2012. PMID: 22820643 Free PMC article.

2

FAK Inhibitor-Based Combinations with MEK or PKC Inhibitors Trigger Synergistic Antitumor Effects in Uveal Melanoma.

Tarin M, Némati F, Decaudin D, Canbezdi C, Marande B, Silva L, Derrien H, Jochemsen AG, Gardrat S, Piperno-Neumann S, Rodrigues M, Mariani P, Cassoux N, Stern MH, Roman-Roman S, Alsafadi S. Tarin M, et al. Among authors: jochemsen ag. Cancers (Basel). 2023 Apr 13;15(8):2280. doi: 10.3390/cancers15082280. Cancers (Basel). 2023. PMID: 37190207 Free PMC article.

3

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53.

Parant J, Chavez-Reyes A, Little NA, Yan W, Reinke V, Jochemsen AG, Lozano G. Parant J, et al. Among authors: jochemsen ag. Nat Genet. 2001 Sep;29(1):92-5. doi: 10.1038/ng714. Nat Genet. 2001. PMID: 11528400

4

Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development.

Migliorini D, Lazzerini Denchi E, Danovi D, Jochemsen A, Capillo M, Gobbi A, Helin K, Pelicci PG, Marine JC. Migliorini D, et al. Among authors: jochemsen a. Mol Cell Biol. 2002 Aug;22(15):5527-38. doi: 10.1128/MCB.22.15.5527-5538.2002. Mol Cell Biol. 2002. PMID: 12101245 Free PMC article.

5

Critical role for a central part of Mdm2 in the ubiquitylation of p53.

Meulmeester E, Frenk R, Stad R, de Graaf P, Marine JC, Vousden KH, Jochemsen AG. Meulmeester E, et al. Mol Cell Biol. 2003 Jul;23(14):4929-38. doi: 10.1128/MCB.23.14.4929-4938.2003. Mol Cell Biol. 2003. PMID: 12832478 Free PMC article.

6

Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity.

Danovi D, Meulmeester E, Pasini D, Migliorini D, Capra M, Frenk R, de Graaf P, Francoz S, Gasparini P, Gobbi A, Helin K, Pelicci PG, Jochemsen AG, Marine JC. Danovi D, et al. Among authors: jochemsen ag. Mol Cell Biol. 2004 Jul;24(13):5835-43. doi: 10.1128/MCB.24.13.5835-5843.2004. Mol Cell Biol. 2004. PMID: 15199139 Free PMC article.

7

Mdmx and Mdm2: brothers in arms?

Marine JC, Jochemsen AG. Marine JC, et al. Cell Cycle. 2004 Jul;3(7):900-4. Epub 2004 Jul 2. Cell Cycle. 2004. PMID: 15254433 Review.

8

Mdmx as an essential regulator of p53 activity.

Marine JC, Jochemsen AG. Marine JC, et al. Biochem Biophys Res Commun. 2005 Jun 10;331(3):750-60. doi: 10.1016/j.bbrc.2005.03.151. Biochem Biophys Res Commun. 2005. PMID: 15865931 Review.

9

DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.

Okamoto K, Kashima K, Pereg Y, Ishida M, Yamazaki S, Nota A, Teunisse A, Migliorini D, Kitabayashi I, Marine JC, Prives C, Shiloh Y, Jochemsen AG, Taya Y. Okamoto K, et al. Among authors: jochemsen ag. Mol Cell Biol. 2005 Nov;25(21):9608-20. doi: 10.1128/MCB.25.21.9608-9620.2005. Mol Cell Biol. 2005. PMID: 16227609 Free PMC article.

10

Inactivation of the p53 pathway in retinoblastoma.

Laurie NA, Donovan SL, Shih CS, Zhang J, Mills N, Fuller C, Teunisse A, Lam S, Ramos Y, Mohan A, Johnson D, Wilson M, Rodriguez-Galindo C, Quarto M, Francoz S, Mendrysa SM, Guy RK, Marine JC, Jochemsen AG, Dyer MA. Laurie NA, et al. Among authors: jochemsen ag. Nature. 2006 Nov 2;444(7115):61-6. doi: 10.1038/nature05194. Nature. 2006. PMID: 17080083

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