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Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite.
Park DJ, Lukens AK, Neafsey DE, Schaffner SF, Chang HH, Valim C, Ribacke U, Van Tyne D, Galinsky K, Galligan M, Becker JS, Ndiaye D, Mboup S, Wiegand RC, Hartl DL, Sabeti PC, Wirth DF, Volkman SK. Park DJ, et al. Among authors: galinsky k. Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):13052-7. doi: 10.1073/pnas.1210585109. Epub 2012 Jul 23. Proc Natl Acad Sci U S A. 2012. PMID: 22826220 Free PMC article.
Hybrid selection for sequencing pathogen genomes from clinical samples.
Melnikov A, Galinsky K, Rogov P, Fennell T, Van Tyne D, Russ C, Daniels R, Barnes KG, Bochicchio J, Ndiaye D, Sene PD, Wirth DF, Nusbaum C, Volkman SK, Birren BW, Gnirke A, Neafsey DE. Melnikov A, et al. Among authors: galinsky k. Genome Biol. 2011 Aug 11;12(8):R73. doi: 10.1186/gb-2011-12-8-r73. Genome Biol. 2011. PMID: 21835008 Free PMC article.
Diversity-oriented synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors.
Lukens AK, Heidebrecht RW Jr, Mulrooney C, Beaudoin JA, Comer E, Duvall JR, Fitzgerald ME, Masi D, Galinsky K, Scherer CA, Palmer M, Munoz B, Foley M, Schreiber SL, Wiegand RC, Wirth DF. Lukens AK, et al. Among authors: galinsky k. J Infect Dis. 2015 Apr 1;211(7):1097-103. doi: 10.1093/infdis/jiu565. Epub 2014 Oct 21. J Infect Dis. 2015. PMID: 25336726 Free PMC article.
Development of a single nucleotide polymorphism barcode to genotype Plasmodium vivax infections.
Baniecki ML, Faust AL, Schaffner SF, Park DJ, Galinsky K, Daniels RF, Hamilton E, Ferreira MU, Karunaweera ND, Serre D, Zimmerman PA, Sá JM, Wellems TE, Musset L, Legrand E, Melnikov A, Neafsey DE, Volkman SK, Wirth DF, Sabeti PC. Baniecki ML, et al. Among authors: galinsky k. PLoS Negl Trop Dis. 2015 Mar 17;9(3):e0003539. doi: 10.1371/journal.pntd.0003539. eCollection 2015 Mar. PLoS Negl Trop Dis. 2015. PMID: 25781890 Free PMC article.
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.
Herman JD, Pepper LR, Cortese JF, Estiu G, Galinsky K, Zuzarte-Luis V, Derbyshire ER, Ribacke U, Lukens AK, Santos SA, Patel V, Clish CB, Sullivan WJ Jr, Zhou H, Bopp SE, Schimmel P, Lindquist S, Clardy J, Mota MM, Keller TL, Whitman M, Wiest O, Wirth DF, Mazitschek R. Herman JD, et al. Among authors: galinsky k. Sci Transl Med. 2015 May 20;7(288):288ra77. doi: 10.1126/scitranslmed.aaa3575. Sci Transl Med. 2015. PMID: 25995223 Free PMC article.
The malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum.
Neafsey DE, Galinsky K, Jiang RH, Young L, Sykes SM, Saif S, Gujja S, Goldberg JM, Young S, Zeng Q, Chapman SB, Dash AP, Anvikar AR, Sutton PL, Birren BW, Escalante AA, Barnwell JW, Carlton JM. Neafsey DE, et al. Among authors: galinsky k. Nat Genet. 2012 Sep;44(9):1046-50. doi: 10.1038/ng.2373. Epub 2012 Aug 5. Nat Genet. 2012. PMID: 22863733 Free PMC article.
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