Thomas TP - Search Results

1

Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic.

Thomas TP, Huang B, Choi SK, Silpe JE, Kotlyar A, Desai AM, Zong H, Gam J, Joice M, Baker JR Jr. Thomas TP, et al. Mol Pharm. 2012 Sep 4;9(9):2669-2676. doi: 10.1021/mp3002232. Epub 2012 Aug 7. Mol Pharm. 2012. PMID: 22827500 Free PMC article.

2

Dendrimer-based targeted delivery of an apoptotic sensor in cancer cells.

Myc A, Majoros IJ, Thomas TP, Baker JR Jr. Myc A, et al. Among authors: thomas tp. Biomacromolecules. 2007 Jan;8(1):13-8. doi: 10.1021/bm060815l. Biomacromolecules. 2007. PMID: 17206782

3

Preclinical antitumor efficacy evaluation of dendrimer-based methotrexate conjugates.

Myc A, Douce TB, Ahuja N, Kotlyar A, Kukowska-Latallo J, Thomas TP, Baker JR Jr. Myc A, et al. Among authors: thomas tp. Anticancer Drugs. 2008 Feb;19(2):143-9. doi: 10.1097/CAD.0b013e3282f28842. Anticancer Drugs. 2008. PMID: 18176110

4

Dendrimer-based tumor cell targeting of fibroblast growth factor-1.

Thomas TP, Shukla R, Kotlyar A, Kukowska-Latallo J, Baker JR Jr. Thomas TP, et al. Bioorg Med Chem Lett. 2010 Jan 15;20(2):700-3. doi: 10.1016/j.bmcl.2009.11.065. Epub 2009 Dec 3. Bioorg Med Chem Lett. 2010. PMID: 19962894 Free PMC article.

5

Targeted dendrimeric anticancer prodrug: a methotrexate-folic acid-poly(amidoamine) conjugate and a novel, rapid, "one pot" synthetic approach.

Zhang Y, Thomas TP, Desai A, Zong H, Leroueil PR, Majoros IJ, Baker JR Jr. Zhang Y, et al. Among authors: thomas tp. Bioconjug Chem. 2010 Mar 17;21(3):489-95. doi: 10.1021/bc9003958. Epub 2010 Feb 3. Bioconjug Chem. 2010. PMID: 20128612 Free PMC article.

6

Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted delivery.

Thomas TP, Choi SK, Li MH, Kotlyar A, Baker JR Jr. Thomas TP, et al. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5191-4. doi: 10.1016/j.bmcl.2010.07.005. Epub 2010 Jul 8. Bioorg Med Chem Lett. 2010. PMID: 20659800 Free PMC article.

7

HER2 specific delivery of methotrexate by dendrimer conjugated anti-HER2 mAb.

Shukla R, Thomas TP, Desai AM, Kotlyar A, Park SJ, Baker JR. Shukla R, et al. Among authors: thomas tp. Nanotechnology. 2008 Jul 23;19(29):295102. doi: 10.1088/0957-4484/19/29/295102. Epub 2008 Jun 10. Nanotechnology. 2008. PMID: 20686639 Free PMC article.

8

Design, synthesis, and biological functionality of a dendrimer-based modular drug delivery platform.

Mullen DG, McNerny DQ, Desai A, Cheng XM, Dimaggio SC, Kotlyar A, Zhong Y, Qin S, Kelly CV, Thomas TP, Majoros I, Orr BG, Baker JR, Banaszak Holl MM. Mullen DG, et al. Among authors: thomas tp. Bioconjug Chem. 2011 Apr 20;22(4):679-89. doi: 10.1021/bc100360v. Epub 2011 Mar 22. Bioconjug Chem. 2011. PMID: 21425790 Free PMC article.

9

Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer-methotrexate conjugate as a potential anticancer agent.

Zhang Y, Thomas TP, Lee KH, Li M, Zong H, Desai AM, Kotlyar A, Huang B, Holl MM, Baker JR Jr. Zhang Y, et al. Among authors: thomas tp. Bioorg Med Chem. 2011 Apr 15;19(8):2557-64. doi: 10.1016/j.bmc.2011.03.019. Epub 2011 Mar 12. Bioorg Med Chem. 2011. PMID: 21459000 Free PMC article.

10

Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis.

Thomas TP, Goonewardena SN, Majoros IJ, Kotlyar A, Cao Z, Leroueil PR, Baker JR Jr. Thomas TP, et al. Arthritis Rheum. 2011 Sep;63(9):2671-80. doi: 10.1002/art.30459. Arthritis Rheum. 2011. PMID: 21618461 Free PMC article.

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