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Adeno-associated virus serotype 9 administered systemically after reperfusion preferentially targets cardiomyocytes in the infarct border zone with pharmacodynamics suitable for the attenuation of left ventricular remodeling.
Konkalmatt PR, Wang F, Piras BA, Xu Y, O'Connor DM, Beyers RJ, Epstein FH, Annex BH, Hossack JA, French BA. Konkalmatt PR, et al. Among authors: piras ba. J Gene Med. 2012 Sep-Oct;14(9-10):609-20. doi: 10.1002/jgm.2673. J Gene Med. 2012. PMID: 23065925 Free PMC article.
Heart Rate Reduction With Ivabradine Protects Against Left Ventricular Remodeling by Attenuating Infarct Expansion and Preserving Remote-Zone Contractile Function and Synchrony in a Mouse Model of Reperfused Myocardial Infarction.
O'Connor DM, Smith RS, Piras BA, Beyers RJ, Lin D, Hossack JA, French BA. O'Connor DM, et al. Among authors: piras ba. J Am Heart Assoc. 2016 Apr 22;5(4):e002989. doi: 10.1161/JAHA.115.002989. J Am Heart Assoc. 2016. PMID: 27107133 Free PMC article.
T₂ -weighted MRI of post-infarct myocardial edema in mice.
Beyers RJ, Smith RS, Xu Y, Piras BA, Salerno M, Berr SS, Meyer CH, Kramer CM, French BA, Epstein FH. Beyers RJ, et al. Among authors: piras ba. Magn Reson Med. 2012 Jan;67(1):201-9. doi: 10.1002/mrm.22975. Epub 2011 May 31. Magn Reson Med. 2012. PMID: 21630350 Free PMC article.
14 results