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Comparison of three amyloid assembly inhibitors: the sugar scyllo-inositol, the polyphenol epigallocatechin gallate, and the molecular tweezer CLR01.
Sinha S, Du Z, Maiti P, Klärner FG, Schrader T, Wang C, Bitan G. Sinha S, et al. ACS Chem Neurosci. 2012 Jun 20;3(6):451-8. doi: 10.1021/cn200133x. Epub 2012 Mar 7. ACS Chem Neurosci. 2012. PMID: 22860214 Free PMC article.
Many compounds have been tested as inhibitors or modulators of amyloid beta-protein (Abeta) assembly in hope that they would lead to effective, disease-modifying therapy for Alzheimer's disease (AD). These compounds typically were either designed to break apart beta-sheets …
Many compounds have been tested as inhibitors or modulators of amyloid beta-protein (Abeta) assembly in hope that they would lead to effecti …
A novel "molecular tweezer" inhibitor of α-synuclein neurotoxicity in vitro and in vivo.
Prabhudesai S, Sinha S, Attar A, Kotagiri A, Fitzmaurice AG, Lakshmanan R, Ivanova MI, Loo JA, Klärner FG, Schrader T, Stahl M, Bitan G, Bronstein JM. Prabhudesai S, et al. Among authors: sinha s. Neurotherapeutics. 2012 Apr;9(2):464-76. doi: 10.1007/s13311-012-0105-1. Neurotherapeutics. 2012. PMID: 22373667 Free PMC article.
Rational design of β-sheet ligands against Aβ42-induced toxicity.
Hochdörffer K, März-Berberich J, Nagel-Steger L, Epple M, Meyer-Zaika W, Horn AH, Sticht H, Sinha S, Bitan G, Schrader T. Hochdörffer K, et al. Among authors: sinha s. J Am Chem Soc. 2011 Mar 30;133(12):4348-58. doi: 10.1021/ja107675n. Epub 2011 Mar 7. J Am Chem Soc. 2011. PMID: 21381732
Disentangling Sources of Momentum Fluctuations in Xe+Xe and Pb+Pb Collisions with the ATLAS Detector.
Aad G, Aakvaag E, Abbott B, Abdelhameed S, Abeling K, Abicht NJ, Abidi SH, Aboelela M, Aboulhorma A, Abramowicz H, Abreu H, Abulaiti Y, Acharya BS, Ackermann A, Adam Bourdarios C, Adamczyk L, Addepalli SV, Addison MJ, Adelman J, Adiguzel A, Adye T, Affolder AA, Afik Y, Agaras MN, Agarwala J, Aggarwal A, Agheorghiesei C, Ahmadov F, Ahmed WS, Ahuja S, Ai X, Aielli G, Aikot A, Ait Tamlihat M, Aitbenchikh B, Akbiyik M, Åkesson TPA, Akimov AV, Akiyama D, Akolkar NN, Aktas S, Al Khoury K, Alberghi GL, Albert J, Albicocco P, Albouy GL, Alderweireldt S, Alegria ZL, Aleksa M, Aleksandrov IN, Alexa C, Alexopoulos T, Alfonsi F, Algren M, Alhroob M, Ali B, Ali HMJ, Ali S, Alibocus SW, Aliev M, Alimonti G, Alkakhi W, Allaire C, Allbrooke BMM, Allen JF, Allendes Flores CA, Allport PP, Aloisio A, Alonso F, Alpigiani C, Alsolami ZMK, Alvarez Estevez M, Alvarez Fernandez A, Alves Cardoso M, Alviggi MG, Aly M, Amaral Coutinho Y, Ambler A, Amelung C, Amerl M, Ames CG, Amidei D, Amini B, Amirie KJ, Amor Dos Santos SP, Amos KR, An S, Ananiev V, Anastopoulos C, Andeen T, Anders JK, Anderson AC, Andrean SY, Andreazza A, Angelidakis S, Angerami A, Anisenkov AV, Annovi A, Antel C, Antipov E, Antonelli M, … See abstract for full author list ➔ Aad G, et al. Among authors: sinha s. Phys Rev Lett. 2024 Dec 20;133(25):252301. doi: 10.1103/PhysRevLett.133.252301. Phys Rev Lett. 2024. PMID: 39752696
Basic Science and Pathogenesis.
Dutta A, Broome J, Sinha S, Gibbons LE, Shade LM, Katsumata Y, Travaglini KJ, Gabitto MI, Zhao Z, Lu Q, Schneider JA, Latimer CS, Keene CD, Crane PK, Fardo DW, Mukherjee S. Dutta A, et al. Among authors: sinha s. Alzheimers Dement. 2024 Dec;20 Suppl 1:e093129. doi: 10.1002/alz.093129. Alzheimers Dement. 2024. PMID: 39750880
6,832 results