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The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB.
Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV, Wen H, Davis BK, Allen IC, Holl EK, Ye Z, Rahman AH, Conti BJ, Eitas TK, Koller BH, Ting JP. Schneider M, et al. Among authors: roberts ra. Nat Immunol. 2012 Sep;13(9):823-31. doi: 10.1038/ni.2378. Epub 2012 Aug 5. Nat Immunol. 2012. PMID: 22863753 Free PMC article.
Cutting edge: NLRC5-dependent activation of the inflammasome.
Davis BK, Roberts RA, Huang MT, Willingham SB, Conti BJ, Brickey WJ, Barker BR, Kwan M, Taxman DJ, Accavitti-Loper MA, Duncan JA, Ting JP. Davis BK, et al. Among authors: roberts ra. J Immunol. 2011 Feb 1;186(3):1333-7. doi: 10.4049/jimmunol.1003111. Epub 2010 Dec 29. J Immunol. 2011. PMID: 21191067 Free PMC article.
Nanoparticle clearance is governed by Th1/Th2 immunity and strain background.
Jones SW, Roberts RA, Robbins GR, Perry JL, Kai MP, Chen K, Bo T, Napier ME, Ting JP, Desimone JM, Bear JE. Jones SW, et al. Among authors: roberts ra. J Clin Invest. 2013 Jul;123(7):3061-73. doi: 10.1172/JCI66895. Epub 2013 Jun 17. J Clin Invest. 2013. PMID: 23778144 Free PMC article.
226 results