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Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.
Steele JW, Ju S, Lachenmayer ML, Liken J, Stock A, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, Wang R, Ringe D, Protter AA, Martins RN, Ehrlich ME, Yue Z, Petsko GA, Gandy S. Steele JW, et al. Among authors: gandy s. Mol Psychiatry. 2013 Aug;18(8):882-8. doi: 10.1038/mp.2012.115. Epub 2012 Aug 7. Mol Psychiatry. 2013. PMID: 22869031 Free PMC article.
Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides.
Xu H, Gouras GK, Greenfield JP, Vincent B, Naslund J, Mazzarelli L, Fried G, Jovanovic JN, Seeger M, Relkin NR, Liao F, Checler F, Buxbaum JD, Chait BT, Thinakaran G, Sisodia SS, Wang R, Greengard P, Gandy S. Xu H, et al. Among authors: gandy s. Nat Med. 1998 Apr;4(4):447-51. doi: 10.1038/nm0498-447. Nat Med. 1998. PMID: 9546791
Generation and regulation of beta-amyloid peptide variants by neurons.
Gouras GK, Xu H, Jovanovic JN, Buxbaum JD, Wang R, Greengard P, Relkin NR, Gandy S. Gouras GK, et al. Among authors: gandy s. J Neurochem. 1998 Nov;71(5):1920-5. doi: 10.1046/j.1471-4159.1998.71051920.x. J Neurochem. 1998. PMID: 9798916 Free article.
456 results