Qin J - Search Results

1

Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimization.

Kong X, Qin J, Li Z, Vultur A, Tong L, Feng E, Rajan G, Liu S, Lu J, Liang Z, Zheng M, Zhu W, Jiang H, Herlyn M, Liu H, Marmorstein R, Luo C. Kong X, et al. Among authors: qin j. Org Biomol Chem. 2012 Sep 28;10(36):7402-17. doi: 10.1039/c2ob26081f. Org Biomol Chem. 2012. PMID: 22875039 Free PMC article.

2

Identification of a novel family of BRAF(V600E) inhibitors.

Qin J, Xie P, Ventocilla C, Zhou G, Vultur A, Chen Q, Liu Q, Herlyn M, Winkler J, Marmorstein R. Qin J, et al. J Med Chem. 2012 Jun 14;55(11):5220-30. doi: 10.1021/jm3004416. Epub 2012 May 18. J Med Chem. 2012. PMID: 22537109 Free PMC article.

3

Identification and synthesis of N-(thiophen-2-yl) benzamide derivatives as BRAF(V600E) inhibitors.

Xie Y, Chen X, Qin J, Kong X, Ye F, Jiang Y, Liu H, Jiang H, Marmorstein R, Luo C. Xie Y, et al. Among authors: qin j. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2306-12. doi: 10.1016/j.bmcl.2013.02.072. Epub 2013 Feb 26. Bioorg Med Chem Lett. 2013. PMID: 23489628 Free PMC article.

4

Development of organometallic S6K1 inhibitors.

Qin J, Rajaratnam R, Feng L, Salami J, Barber-Rotenberg JS, Domsic J, Reyes-Uribe P, Liu H, Dang W, Berger SL, Villanueva J, Meggers E, Marmorstein R. Qin J, et al. J Med Chem. 2015 Jan 8;58(1):305-14. doi: 10.1021/jm5011868. Epub 2014 Nov 13. J Med Chem. 2015. PMID: 25356520 Free PMC article.

5

The crystal structure of BRAF in complex with an organoruthenium inhibitor reveals a mechanism for inhibition of an active form of BRAF kinase.

Xie P, Streu C, Qin J, Bregman H, Pagano N, Meggers E, Marmorstein R. Xie P, et al. Among authors: qin j. Biochemistry. 2009 Jun 16;48(23):5187-98. doi: 10.1021/bi802067u. Biochemistry. 2009. PMID: 19371126 Free PMC article.

6

Synthesis, crystal structures, molecular docking, and in vitro biological activities of transition metals with 4-(2,3-dichlorophenyl)piperazine-1-carboxylic acid.

Yang DD, Chen YN, Wu YS, Wang R, Chen ZJ, Qin J, Qian SS, Zhu HL. Yang DD, et al. Among authors: qin j. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3295-3299. doi: 10.1016/j.bmcl.2016.05.051. Epub 2016 May 19. Bioorg Med Chem Lett. 2016. PMID: 27241690

7

Design, synthesis and molecular docking of 1,4-benzodioxane thiazolidinedione piperazine derivatives as FabH inhibitors.

Sun J, He W, Liu HY, Qin J, Ye CL. Sun J, et al. Among authors: qin j. Bioorg Chem. 2019 Jul;88:102958. doi: 10.1016/j.bioorg.2019.102958. Epub 2019 Apr 29. Bioorg Chem. 2019. PMID: 31054434

8

Preparations, characterization, and biological features of mononuclear Cu(II) complexes based on hydrazone ligands.

Qin J, Zhao SS, Liu YP, Man ZW, Wang P, Wang LN, Xu Y, Zhu HL. Qin J, et al. Bioorg Med Chem Lett. 2016 Oct 15;26(20):4925-4929. doi: 10.1016/j.bmcl.2016.09.015. Epub 2016 Sep 7. Bioorg Med Chem Lett. 2016. PMID: 27634193

9

Microbiota analysis of perimenopausal women experiencing recurrent vaginitis in conjunction with urinary tract infection.

Bi Y, Wang Y, Li W, Chen Y, Qin J, Zheng H. Bi Y, et al. Among authors: qin j. BMC Microbiol. 2025 Jan 4;25(1):1. doi: 10.1186/s12866-024-03709-3. BMC Microbiol. 2025. PMID: 39755613

10

Low-Intensity Pulsed Ultrasound Delays the Onset of Osteoporosis and Dyslipidemia in Mice With Premature Ovarian Insufficiency.

Deng J, Li J, Han X, Zhou Y, He S, Xu J, Qin J, Song G, Xiao X, Wu L, Wang Y. Deng J, et al. Among authors: qin j. J Ultrasound Med. 2025 Jan 4. doi: 10.1002/jum.16641. Online ahead of print. J Ultrasound Med. 2025. PMID: 39754744

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