Louw AI - Search Results

1

Polyamine uptake by the intraerythrocytic malaria parasite, Plasmodium falciparum.

Niemand J, Louw AI, Birkholtz L, Kirk K. Niemand J, et al. Among authors: louw ai. Int J Parasitol. 2012 Sep;42(10):921-9. doi: 10.1016/j.ijpara.2012.07.005. Epub 2012 Aug 2. Int J Parasitol. 2012. PMID: 22878129

2

Biochemical characterisation and novel classification of monofunctional S-adenosylmethionine decarboxylase of Plasmodium falciparum.

Williams M, Sprenger J, Human E, Al-Karadaghi S, Persson L, Louw AI, Birkholtz LM. Williams M, et al. Among authors: louw ai. Mol Biochem Parasitol. 2011 Nov;180(1):17-26. doi: 10.1016/j.molbiopara.2011.07.004. Epub 2011 Jul 22. Mol Biochem Parasitol. 2011. PMID: 21803076

3

Anthracene-polyamine conjugates inhibit in vitro proliferation of intraerythrocytic Plasmodium falciparum parasites.

Niemand J, Burger P, Verlinden BK, Reader J, Joubert AM, Kaiser A, Louw AI, Kirk K, Phanstiel O 4th, Birkholtz LM. Niemand J, et al. Among authors: louw ai. Antimicrob Agents Chemother. 2013 Jun;57(6):2874-7. doi: 10.1128/AAC.00106-13. Epub 2013 Apr 1. Antimicrob Agents Chemother. 2013. PMID: 23545535 Free PMC article.

4

Functional consequences of perturbing polyamine metabolism in the malaria parasite, Plasmodium falciparum.

Clark K, Niemand J, Reeksting S, Smit S, van Brummelen AC, Williams M, Louw AI, Birkholtz L. Clark K, et al. Among authors: louw ai. Amino Acids. 2010 Feb;38(2):633-44. doi: 10.1007/s00726-009-0424-7. Epub 2009 Dec 9. Amino Acids. 2010. PMID: 19997948 Review.

5

In vitro inhibition of Plasmodium falciparum early and late stage gametocyte viability by extracts from eight traditionally used South African plant species.

Moyo P, Botha ME, Nondaba S, Niemand J, Maharaj VJ, Eloff JN, Louw AI, Birkholtz L. Moyo P, et al. Among authors: louw ai. J Ethnopharmacol. 2016 Jun 5;185:235-42. doi: 10.1016/j.jep.2016.03.036. Epub 2016 Mar 16. J Ethnopharmacol. 2016. PMID: 26994818

6

Resisting resistance: is there a solution for malaria?

Verlinden BK, Louw A, Birkholtz LM. Verlinden BK, et al. Expert Opin Drug Discov. 2016;11(4):395-406. doi: 10.1517/17460441.2016.1154037. Epub 2016 Feb 29. Expert Opin Drug Discov. 2016. PMID: 26926843 Review.

7

Structural and mechanistic insights into the action of Plasmodium falciparum spermidine synthase.

Burger PB, Birkholtz LM, Joubert F, Haider N, Walter RD, Louw AI. Burger PB, et al. Among authors: louw ai. Bioorg Med Chem. 2007 Feb 15;15(4):1628-37. doi: 10.1016/j.bmc.2006.12.017. Epub 2006 Dec 13. Bioorg Med Chem. 2007. PMID: 17196392

8

Deletion mutagenesis of large areas in Plasmodium falciparum genes: a comparative study.

Williams M, Louw AI, Birkholtz LM. Williams M, et al. Among authors: louw ai. Malar J. 2007 May 22;6:64. doi: 10.1186/1475-2875-6-64. Malar J. 2007. PMID: 17519001 Free PMC article.

9

Transcriptional responses of Plasmodium falciparum to alpha-difluoromethylornithine-induced polyamine depletion.

Clark K, Dhoogra M, Louw AI, Birkholtz LM. Clark K, et al. Among authors: louw ai. Biol Chem. 2008 Feb;389(2):111-25. doi: 10.1515/BC.2008.014. Biol Chem. 2008. PMID: 18163886

10

Co-inhibition of Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase reveals perturbation-specific compensatory mechanisms by transcriptome, proteome, and metabolome analyses.

van Brummelen AC, Olszewski KL, Wilinski D, Llinás M, Louw AI, Birkholtz LM. van Brummelen AC, et al. Among authors: louw ai. J Biol Chem. 2009 Feb 13;284(7):4635-46. doi: 10.1074/jbc.M807085200. Epub 2008 Dec 10. J Biol Chem. 2009. PMID: 19073607 Free PMC article.

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